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excision

The removal of a section of double-stranded DNA that is faulty due to mutation or incorrect replication. The process includes incision, i.e. cleavage of the strand by an endonuclease and the action of a 5'-nucleotidase, followed by filling in by a polymerase and ligation. The E. coli DNA polymerase I has all these activities. (see also proofreading (editing))
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