GABA shunt An alternative route from -oxoglutarate to succinyl-CoA as part of the tricarboxylic acid cycle. Rather than going through the -oxoglutarate dehydrogenase reaction, -oxoglutarate condenses with NH3 to form -iminoglutarate, then is reduced to glutamic acid, decarboxylated to -aminobutyrate (GABA), transaminated to succinic semialdehyde and oxidized to succinyl-CoA.
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