motif A recurring pattern of protein folding, e.g. a homeobox, a zinc finger. A higher order of protein structure is a module which consists of several motifs and units of secondary structure; in particular cases, it may be equivalent to a domain, which in a globular protein is a region that has its own tertiary structure, is stable independently of the rest of the protein and is often connected to other domains of the same protein by short sequences without secondary structure.Bork, P. and Koonin, E.V. (1996) Curr. Opin. Struct. Biol. 6, 366-376; Henikoff, S., Greene, E.A., Pietrokovski, S., Bork, P., Attwood, T.K. and Hood, L. (1997) Science 278, 609-614
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