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spliceosome A complex of (small nuclear RNA)-protein complexes and other proteins that assemble on a pre-mRNA and catalyse the excision of an intron in a process mechanistically similar to group II self-splicing. It acts presumably by forcing the intron into a loop and bridging the pre-mRNA at its splicing sites. Wise, J.A. (1993) Science 262, 1978-1979

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