Z-DNA
A left-handed variant of the DNA double helix originally observed in a sequence of alternating G and C bases, but possible in sequences of alternating purine and pyrimidine bases. The purines are 'flipped' 1808 about the glycosidic bond to assume the syn conformation (as opposed to B-form DNA, in which they assume the anti conformation); the pyrimidines remain in the anti conformation. (see also A-DNA; B-DNA)Herbert, A. and Rich, A. (1996) J. Biol. Chem. 271, 11595-11598
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