zonation
The phenomenon by which specific areas of an organ have characteristic metabolic functions; e.g. Alanine aminotransferase activity is relatively high in the cells of the liver served by the portal blood supply (the periportal region) whereas glutamate dehydrogenase activity is relatively high in the cells that feed the hepatic vein (the perivenous region), and glutamine hydrolysis and urea synthesis are prominent in the periportal region while glutamine synthesis is prominent in the perivenous region. Quistorff, B. (1990) Essays Biochem. 25, 83-136
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