zone of adhesion
An area of a lipid bilayer where inner and outer leaflets join, and by which proteins, gangliosides and other products may be targeted to the outer surface of the plasma membrane from their cytoplasmic sites of biosynthesis. Models postulate that such zones are continuous, e.g. they surround a pore through the membrane, or occur stepwise via a vesicle formed by the pinching off into the inter-leaflet space of part of the membrane inner leaflet, which can then fuse with the membrane outer leaflet. Raetz, C.H.R. (1990) Annu. Rev. Biochem. 59, 129-170
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