charge In chemistry, the integral sum of positive and negative particles that make up a species, a cation if the charge is positive, an anion, if the charge is negative. In biochemistry, the loading of a binding site with its intended ligand, e.g. the appropriate amino acid bound to its tRNA; in cell biology, essentially as in biochemistry, but on a macromolecular level, e.g. the charging of a liposome with material for transport cross a cell membrane.
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