cloverleaf The formalized pattern assumed by a tRNA molecule viewed in two dimensions that shows the regions of internal complementarity that allow the polynucleotide to fold back upon itself into base-paired double helices. The stem includes the acceptor stem at the 3'-end, which attaches the amino acid, and the non-complementary loops or ARMS include the anticodon arm, which hybridizes with the codon of an mRNA. In three dimensions the structure can be divided into two sections at a right angle to one another: a coaxial stack that includes the acceptor stem, and the remainder of the molecule, i.e. the common arm that is shared by the two sections.Pace, N.R. and Smith, D. (1990) J. Biol. Chem. 265, 3587-3590
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