DNA methylation A phenomenon that represses expression of regions of the genome. Transcription is prevented when the DNA is methylated and folded into nucleosomes. Eukaryotic DNA is methylated almost exclusively as 5-methyl cytosine; prokaryotic DNA is methylated also as 6-methyl adenosine. (see also imprinting)Kass, S.U., Landsberger, N. and Wolffe, A.P. (1997) Curr. Biol. 7, 157-165
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