HCV NS3, Hepatitis C Virus Antigen, Recombinant

Full Name

Abbreviated Name-1

HCV-NS3; Hepatitis C Virus NS3

Documents
Figures
Reference
Iwai A, et al. Hepatitis C virus nonstructural protein NS3 binds to Sm-D1, a small nuclear ribonucleoprotein associated with autoimmune disease. Microbiol. Immunol. 2003; 47(8): 601-611. Kanistanon D, et al. Hepatitis C virus nonstructural 3 protein: recombinant NS3 protein of the Thai isolates as an antigen in a diagnostic assay. Asian Pac. J. Allergy Immunol. Sep 2002; 20(3): 161-166. Borowski P, et al. Nonstructural protein 3 of hepatitis C virus blocks the distribution of the free catalytic subunit of cyclic AMP-dependent protein kinase. J. Virol. Apr 1997; 71(4): 2838-2843.

Description

Hepatitis C Virus (HCV) NS3 is an E. coli-derived recombinant. The protein Hepatitis C Virus (HCV) NS3 contains the full-length HCV NS3 (c33c) immunodominant regions and carries a His6-Tag. No fusion sequences.

Source

E. coli

M.W.

26,224.83 Da (None fusion)

Purity

Protein is >95% pure as determined by 10% PAGE (coomassie staining).

Storage

Protein is shipped at ambient temperature. Upon arrival, store at -20°C.

Concentration

1 mg/vial, in 50 mM Na-PO₄, pH 8.3, 8 mM DTT

Stability

Five years frozen. One month in solution at room temperature.

Specificity

Immunoreactive with sera of HCV-infected individuals, including sera with antibodies to NS3 secondary structure domains.

Applications

Antigen in ELISA and Western blots, excellent antigen for detection of HCV with minimal specificity problems

Note

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Related Products

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Z00042	HCV NS3, Hepatitis C Virus Antigen, Recombinant	1 mg	$1000
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Z00068	HCV NS3 Subtype 2b, Hepatitis C Virus Antigen, Recombinant	1 mg	$1000
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