Epstein-Barr Virus (HHV-4) EA Protein, Recombinant

Full Name

Abbreviated Name-1

EBV (HHV-4) EA;

Documents
Figures
Reference
Gershburg E, Pagano JS. Phosphorylation of the Epstein-Barr virus (EBV) DNA polymerase processivity factor EA-D by the EBV-encoded protein kinase and effects of the L-riboside benzimidazole 1263W94. J. Virol. Feb 2002; 76(3): 998-1003. Chen MR, et al. A protein kinase activity associated with Epstein-Barr virus BGLF4 phosphorylates the viral early antigen EA-D in vitro. J. Virol. Apr 2000; 74(7): 3093-3104.

Description

E. coli derived recombinant. The protein contains the HHV-4 EA regions. Epstein-Barr Virus (EBV) is one of the most common and widely disseminated human viruses, and is the etiological agent of infectious mononucleosis (IM). IM, also called kissing disease because of its prevalence in young adults, may vary from mild to severe - but it is rarely fatal. Mononucleosis must be distinguished from a variety of other infectious diseases that cause fever and inflammation of the upper respiratory tract. A syndrome similar to EBV-induced mononucleosis may be the result of a cytomegalovirus or toxoplasma infection.

Purity

Protein is >95% pure as determined by 10% PAGE (coomassie staining).

Storage

Protein is shipped at ambient temperature. Upon arrival, Store at -20°C. Five years frozen. One month in solution at room temperature.

Concentration

1 mg/ml in 50 mM Tris-HCl, 10 mM glutation, 60 mM NaCl, 0.5% sarcosyl, 50% glycerol.

Specificity

Immunoreactive with sera of EBV-infected individuals.

Applications

Antigen in ELISA and Western blots, excellent antigen for detection of HHV-4 (EBV) with minimal specificity problems.

Note

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