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Insulin Like Growth Factor-1 (IGF-1) (4-70), human

*This product has been discontinued!*
IGF is a well-characterized basic peptide believed to be secreted by the liver and to circulate in the blood. It has growth-regulating, insulin-like, and mitogenic activities. This growth factor has a major, but not absolute, dependence on Somatotropin. It is believed to be mainly active in adults in contrast to Insulin like Growth Factor 2, which is a major fetal growth factor.GenScript Insulin Like Growth Factor (IGF)-1 (4-70), human , produced in E. coli, is a single, non-glycosylated, polypeptide chain containing 67 amino acids and having a molecular mass of 7,372 Da.
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Purity The purity of GenScript Recombinant Human IGF is greater than 95% as determined by the following methods:
(a) HPLC analysis
(b) Anion-exchange FPLC
(c) Reducing and non-reducing SDS-PAGE silver-stained gel analysis
Endotoxin Level The endotoxin level of GenScript Recombinant Human IGF is below 0.1 ng/μg (1 IEU/μg) of IGF-I (4-70).
Formulation IGF-I (4-70) is lyophilized after extensive dialysis against acetic acid buffer.
Reconstitution It is recommended that lyophilized IGF-I (4-70) be stored in 100 mM acetic acid not less than 100 µg/ml, which can then be further diluted to other aqueous solutions.
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Target Background IGF is a well-characterized basic peptide believed to be secreted by the liver and to circulate in the blood. It has growth-regulating, insulin-like, and mitogenic activities. This growth factor has a major, but not absolute, dependence on Somatotropin. It is believed to be mainly active in adults in contrast to Insulin like Growth Factor 2, which is a major fetal growth factor.
GenScript Insulin Like Growth Factor (IGF)-1 (4-70), human , produced in E. coli, is a single, non-glycosylated, polypeptide chain containing 67 amino acids and having a molecular mass of 7,372 Da.
Synonyms rHu IGF-I(4-70), Recombinant Human IGF-I (4-70); Recombinant Insulin-Like Growth Factor-I (4-70)
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