IL-8/CXCL8 (3-79aa), Human

*This product has been discontinued!*

Interleukin-8 (IL-8) belongs to the neutrophil-specific CXC family of chemokines. It is one of the initial cytokines released from a variety of cell types, including T cells, endothelial cells and fibroblasts, in response to an inflammatory stimulus and acts by recruiting neutrophils, T-cells and basophils to the site of inflammation. Elevated Interleukin-8 (IL-8) levels are associated with the onset of a variety of disease states.Human Interleukin-8 (IL-8) (3-79) , produced in E. coli, is a single, non-glycosylated polypeptide chain containing 77 amino acids and having a molecular mass of 8,904 Da.

Cat. No.	Z02189
Size	Buy in bulk

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Product Introduction Background

Product Introduction

Species	Human
Purity	The purity of recombinant Human Interleukin-8 (IL-8) is greater than 95.0%, as determined by the following methods: (a) RP-HPLC analysis (b) Reducing and non-reducing SDS-PAGE silver-stained gel analysis
Endotoxin Level	Less than 0.1ng/µg (1 IEU/µg) determined by LAL test.
Formulation	The protein was lyophilized after extensive dialysis against PBS, pH7.4.
Reconstitution	It is recommended that lyophilized GenScript rHuIL-8 /77 be reconstituted in sterile 18 MΩ-cm H₂O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions.

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Background

Target Background

Interleukin-8 (IL-8) belongs to the neutrophil-specific CXC family of chemokines. It is one of the initial cytokines released from a variety of cell types, including T cells, endothelial cells and fibroblasts, in response to an inflammatory stimulus and acts by recruiting neutrophils, T-cells and basophils to the site of inflammation. Elevated Interleukin-8 (IL-8) levels are associated with the onset of a variety of disease states.
Human Interleukin-8 (IL-8) (3-79) , produced in E. coli, is a single, non-glycosylated polypeptide chain containing 77 amino acids and having a molecular mass of 8,904 Da.

Synonyms

rHu IL-8 (3-79);

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