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Growth Hormone (GH), mouse



Cat. No.
Name
Size   
Price
Selected
Z02192-10
10 μg
$75
Z02192-50
50 μg
$199
Z02192-1
1 mg(2x500 μg)
$1,900

Full Name Growth Hormone (GH), mouse
Abbreviated Name-1
GH (Mouse);
Documents
Growth Hormone (GH), mouseDocument-MSDS: 15128_20111230000406.PDF (PDF)
Description
Growth Hormone (GH), mouse is a member of the somatotropin / prolactin family of hormones which play an important role in growth control. The gene, along with four other related genes, is located at the growth hormone locus on chromosome 17 where they are interspersed in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. The five genes share a remarkably high degree of sequence identity. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed in the pituitary but not in placental tissue as is the case for the other four genes in the growth hormone locus. Mutations in or deletions of the gene lead to growth hormone deficiency and short stature.
GenScript Recombinant Mouse Growth Hormone, produced in E. coli, is a single, non-glycosylated, polypeptide chain containing 191 amino acids and having a molecular mass of 22,000 Da.
Source
E. coli
M.W.
22,000 Da
Purity
The purity of GenScript Recombinant Mouse Growth Hormone is greater than 95% as determined by the following methods:
(a) SEC-HPLC analysis
(b) Reducing and non-reducing SDS-PAGE Silver-Stained gel analysis
Endotoxin Level
The endotoxin level of GenScript Recombinant Mouse Growth Hormone is below 0.1 ng/μg (1 IEU/μg) determined by LAL test.
Storage
Lyophilized Mouse Growth Hormone remains stable at room temperature for three weeks, but it is best stored desiccated below -18°C. Upon reconstitution Mouse Growth Hormone should be stored at 4°C for up to seven days. For long term storage it is recommended that a carrier protein (0.1% HSA or BSA ) be added. Avoid repeated freeze-thaw cycles.
Formulation
The protein was lyophilized after extensive dialysis against 50mM Tris-HCl, pH8.0, 500mM NaCl buffer.
Reconstitution
It is recommended to reconstitute the lyophilized rmGH in sterile 18 MΩ-cm H2O not less than 100 µg/ml, which can then be further diluted to other aqueous solutions.
Specificity
Recombinant mouse growth hormone is fully biologically active when compared to standard human growth hormone which is 3 units/mg.
Sequence
The sequence of the
first five N-terminal amino
acids was determined and
was found to be
Met-Phe-Pro-Ala-Met.
Document-COA
  • 153629_3_Z02192_COA.pdf
  • C50121211_Z02192_COA.pdf
  • C50611310_Z02192_COA.pdf
  • C50791310_Z02192_COA.pdf
  • C50831209_Z02192_COA.pdf
  • C58731306_Z02192_COA.pdf
  • C50121211_Z02192_COA.pdf
  • C50611310_Z02192_COA.pdf
  • C50791310_Z02192_COA.pdf
  • C50831209_Z02192_COA.pdf
  • C58731306_Z02192_COA.pdf
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