Macrophage Colony Stimulating Factor (M-CSF), Human

*This product has been discontinued!*

Macrophage-Colony Stimulating Factor (M-CSF), also known as CSF-1, is a four ª helical bundle cytokine that is the primary regulator of macrophage survival, proliferation and differentiation. Macrophage-Colony Stimulating Factor (M-CSF) is also essential for the survival and proliferation of osteoclast progenitors. Macrophage-Colony Stimulating Factor (M-CSF) also primes and enhances macrophage killing of tumor cells and microorganisms, regulates the release of cytokines and other inflammatory modulators from macrophages, and stimulates pinocytosis.

Cat. No.	Z02723
Size	Buy in bulk

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Product Introduction Background

Product Introduction

Purity	>95% by SDS-PAGE and HPLC analyses.
Endotoxin Level	Less than 1 EU/ug of recombinant human Macrophage Colony Stimulating Factor (M-CSF) as determined by LAL method.
Formulation	Lyophilized from a 0.2µm filtered solution in 20mM PB, containing 1% HSA and 3% Mannitol.
Reconstitution	We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20 °C. Further dilutions should be made in appropriate buffered solutions.

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Background

Target Background

Macrophage-Colony Stimulating Factor (M-CSF), also known as CSF-1, is a four ª helical bundle cytokine that is the primary regulator of macrophage survival, proliferation and differentiation.
Macrophage-Colony Stimulating Factor (M-CSF) is also essential for the survival and proliferation of osteoclast progenitors. Macrophage-Colony Stimulating Factor (M-CSF) also primes and enhances macrophage killing of tumor cells and microorganisms, regulates the release of cytokines and other inflammatory modulators from macrophages, and stimulates pinocytosis.

Synonyms

Macrophage Colony Stimulating Factor (M-CSF), Human;

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