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Macrophage Colony Stimulating Factor (M-CSF), Human

*This product has been discontinued!*
Macrophage-Colony Stimulating Factor (M-CSF), also known as CSF-1, is a four ª helical bundle cytokine that is the primary regulator of macrophage survival, proliferation and differentiation. Macrophage-Colony Stimulating Factor (M-CSF) is also essential for the survival and proliferation of osteoclast progenitors. Macrophage-Colony Stimulating Factor (M-CSF) also primes and enhances macrophage killing of tumor cells and microorganisms, regulates the release of cytokines and other inflammatory modulators from macrophages, and stimulates pinocytosis.
Z02723
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Purity >95% by SDS-PAGE and HPLC analyses.
Endotoxin Level Less than 1 EU/ug of recombinant human Macrophage Colony Stimulating Factor (M-CSF) as determined by LAL method.
Formulation Lyophilized from a 0.2µm filtered solution in 20mM PB, containing 1% HSA and 3% Mannitol.
Reconstitution We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1% BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at < -20 °C. Further dilutions should be made in appropriate buffered solutions.
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Target Background Macrophage-Colony Stimulating Factor (M-CSF), also known as CSF-1, is a four ª helical bundle cytokine that is the primary regulator of macrophage survival, proliferation and differentiation.
Macrophage-Colony Stimulating Factor (M-CSF) is also essential for the survival and proliferation of osteoclast progenitors. Macrophage-Colony Stimulating Factor (M-CSF) also primes and enhances macrophage killing of tumor cells and microorganisms, regulates the release of cytokines and other inflammatory modulators from macrophages, and stimulates pinocytosis.
Synonyms Macrophage Colony Stimulating Factor (M-CSF), Human;
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