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TRAIL Receptor-2, Human



Cat. No.
Name
Size   
Price
Selected
Z03095-1
1 mg
$569

Full Name TRAIL Receptor-2, Human
Abbreviated Name-1
soluble TRAIL Receptor-2, DR5, TNFRSF10B, KILER, TRICK2A, TRICKB
Documents
TRAIL Receptor-2, HumanDocument-MSDS: Z03095_MSDS.pdf (pdf)
Description
TRAIL Receptor-2 is a cell-surface receptor involved in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced cell-death signaling. The death ligand TRAIL bears high potential as a new anticancer agent, as binding to the death receptors TRAIL-R1 or TRAIL-R2 triggers apoptosis in most cancer cells. TRAIL-R2 is associated with a decrease in the survival rates of breast cancer patients.
Source
293
M.W.
~15 kDa, observed by reducing SDS-PAGE.
Purity
> 95% as analyzed by SDS-PAGE and HPLC.
Endotoxin Level
< 0.2 EU/μg, determined by LAL method.
Specific Activity
ED50 < 6 ng/ml, measured in a cell proliferation assay using RPMI-8226 cells in the presence of 25 ng/ml of human TRAIL.
Storage
Lyophilized recombinant Human TRAIL Receptor-2 remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, Human TRAIL Receptor-2 should be stable up to 1 week at 4°C or up to 2 months at -20°C.
Formulation
Lyophilized after extensive dialysis against PBS.
Reconstitution
Reconstituted in ddH2O or PBS at 100 μg/ml.
Sequence
Ala54-Glu182 (accession # Q6FH58).
Note
For research use only
Document-COA
  • B60101307_Z03095_COA.pdf
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