Stable Cell Line Development Services
GenScript's stable cell line service covers all your needs in the aspects of protein/antibody production, and assay development. Not only have we developed cell lines stable at expression level, but also established stable cell lines ready for assay development. Furthermore, GenScript's CellPower™ platform guarantees over-expressing of gene of interest in any cell hosts.
Outline of Stable Cell Line Services
Stable Research Cell Line (SC1260)
Stable Production Cell Line (SC1503)
Stable Industrial Cell Line (SC1557)
Service package(SC1394A & SC1394B)
Refer to Guaranteed Stable Cell Line Service for more details
GenScript utilizes 2-round selection strategy for GPCR and ion channel stable cell line generation upon different applications. To reduce the cost and timeline, GenScript chooses HTS-compatible fluorescence- or luminescence-based assays to screen stable clones in the 1st round selection. In 2nd round selection, radioisotope- and electrophysiology-based assays are available upon your applications. For nuclear receptors, transporters, and other targets which have no ready HTS-compatible assays, GenScript offers mRNA or protein level assays as alternative solutions.
In addition, GenScript can develop a new assay upon your specifications. Please feel free to contact us for technique support.
1st Round Selection
2nd Round Selection
|GPCRs||Gq-coupled||Calcium assay||Radioligand binding assay|
|Gi/Gs-coupled||Calcium assay (Gqi5/Gα15), cAMP assay, or luciferase reporter gene assay|
|Ion Channels||Calcium channels||Calcium assay||Radioligand binding assay or manual patch clamp assay|
|Potassium channels||Thallium flux assay or membrane potential assay|
|Sodium channels||Membrane potential assay|
|Chloride channels||YFP reporter gene assay|
Nuclear Receptors, Transporters, etc.
|Upon client's specifications||Upon client's specifications|
CHO-K1, CHO-K1/Gα15, CHO-K1/Gqi5, HEK293, 293T, 293EC18, 293EC18/CRE-Luc, 1321N1, RH7777, and U-2OS are available as starting cell lines. For special requirements, please feel free to contact us.
For case studies and quotation, please refer to following website: Stable Cell Line for Assay Development
Quotations and Ordering
To request a quotation, please download and complete the Quotation Form, and send it back by email or fax.
- For our protein production mammalian stable cell line development service, please download .
- For our guaranteed stable cell line development service, please give us a
Or refer to Guaranteed Stable Cell Line Service
To order, please send the completed Quotation Form to us by email or fax with a formal PO (Purchase Order) or credit card information. You can also submit PO/credit card information by phone or via our secure online messaging system.
If you are also submitting samples, please mail them together with a hard copy of the completed Quotation Form to the following address: BioProcess Services, GenScript, 860 Centennial Avenue., Piscataway, NJ 08854, US.
Our customer service representatives are available 24 hours a day, Monday through Friday to assist you.