Custom Viral Vector Services

GenScript's long experience in gene synthesis and cloning give us an edge in the area of gene expression. The addition of custom viral vector service to our already strong gene repertoire allows us to offer clients one centralized source of expertise, involving the design, creation, and production of viral vectors for gene expression and transfer. Our services offer a characterized repository of viral vectors, including adenoviral (AV), adeno-associated viral (AAV), lentiviral (LV), and retroviral (RV) vectors.

GenScript has processed hundreds of viral vector requests each year since the department's inception. We continually update our standard operating procedures to incorporate new techniques and technologies into our viral vector portfolio. We use established technology in our viral vector service comprised of solid, safe and proven techniques and technology.

Key Features:

Viral Vector Selection Guide:

GenScript offers four viral vector systems. The genome size, packaging capacity, limitations, and other important features of the four viral vectors are summarized in the table below.

General Viral Vector Construction Procedures:

Although the ideal packaging method for a given gene may vary depending on the viral vector system employed, the general packaging procedure can be summarized as follows:

• Select a viral vector that efficiently transduces target cells without affecting cell viability. In some cases, it is recommended that a pilot study be performed using a vector expressing eGFP or galactosidase reporter.


• Clone the gene of interest and the selected promoter into appropriate shuttle vectors and verify transgene insertion into the shuttle vector by PCR and sequencing.


• Confirm the infectivity of the recombinant virus by transfection assay, and verify transgene expression by ELISA or immunoblot.


• Where possible, it is also advisable to show that the transgene product functions as required before proceeding to virus packaging and preparation.

Quotations and Ordering:

For quotation requests, please download and complete GenScript Viral Vector Services Quotation Request Form, and email or fax it to us with a detailed description of project requirements. For questions, please use our secure web server. However, you may also contact us by email at order@genscript.com, phone, or fax.

Orders can be placed by phone, email, or fax with either a formal PO (Purchase Order) or credit card. Please email or fax us a completed GenScript Viral Vector Services Quotation Request Form. Our customer service representatives are available 24 hours Monday through Friday. If target gene is physically available, please submit your target gene along with a hard copy of completed GenScript Viral Vector Services Quotation Request Form to Viral Vector Services, GenScript Corp., 120 Centennial Ave., Suite 105, Piscataway, NJ 08854, US.

For specific virus services, please try one of the links below:

	Order by email: order@genscript.com
	Order by phone: 1-877-436-7274 (Toll-Free) 1-732-885-9188
	Order by fax: 1-732-210-0262 1-732-885-5878