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CRISPR is revolutionizing the field of gene editing. It has the potential to alter the course of research and drug discovery, by providing scientists with a powerful tool to change any gene, in any cell in a highly targeted manner and without introducing foreign DNA. The benefits of CRISPR/Cas9 over previous forms of gene editing, such as TALENs and zinc finger nuclease (ZFN), are that it is much simpler to implement and has higher efficiency at performing bi-allelic gene modifications.
GenScript is pleased to introduce GenCRISPR™, a full CRISPR-based gene editing service, to produce a genetically modified cell using any mammalian cell line and targeting any gene. Our scientists are experts at performing gene editing with CRISPR, from
designing gRNA constructs for CRISPR to transfection and single clone generation of a wide range of cells, including difficult-to-transfect and tumor cell lines.
EZ Knock-out cell line service (SC1755)
***Validation of full-allelic knock-out cell lines at mRNA or protein level upon request
Customized Knock-out cell line service (SC1652)
16-20 weeks (easy-to-handle lines)
20-26 weeks (difficult-to-handle lines)
Lenti-CRISPR KO Service (SC1652-V)
*It is preferred that customers provide their own cell lines, but cell lines can also be purchased by GenScript for an additional fee.
**Prices may vary based on project specifications
***Validation services for knock-out cell lines can be found under the "Add On Services" tab.
Easy-to-handle and difficult-to-handle cell lines are categorized based on their transfection ability. As compared to Easy-to-handle cell lines, difficult-to-handle cell lines need additional characterization methods including but not limited to: transfection optimization, promoter activity testing, clonality optimization, cell culture establishment, etc.
Our customer service representatives are available 24 hours a day, Monday through Friday, to assist you. However, you may also contact us by email, phone, or fax.
Please contact us if you need immediate assistance.
Please contact us (phone: 1-877-436-7274 or email: firstname.lastname@example.org),if you need immediate assistance.