Synthetic RNA is widely used in research applications as an important tool for gene functional analysis and the development of novel therapeutic strategies. GenScript provides high-quality and cost-effective custom RNA oligos with flexible synthesis scales to meet researchers' different needs. Unmodified RNA, RNA with modifications, chimeric oligonucleotides with mixed DNA and RNA bases, 2'-OMe-RNA, 2'-F-RNA, and other antisense RNAs are available at your specific request. To ensure that the RNA oligos are of highest quality, all RNA oligonucleotides are identified by ESI (electrospray ionization) mass spectrometry. To meet QC specifications, the deviation from measured mass to calculated mass must be no more than 1‰. The purity of the RNA is analyzed by HPLC.

Competitive Advantages

Comprehensive Backbones

RNA, 2'-OMe-RNA, 2'-F-RNA and other analogs

Flexible Synthesis Scales

50 nmol, 100 nmol, 200 nmol, 1 µmol, 5 µmol, and 10 µmol. Bulk orders are available upon request

Experienced Team

scientists and staff with over 20 years of experience in oligo synthesis and modifications

High Quality

ISO9001 certificated, comprehensive quality control reports (HPLC, MS)

Cost Effective

competitive prices, especially at 50 nmol scale

Long RNA oligos up to 160 bases are now available!

ISO9001 certificated, comprehensive quality assurance

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RNA Oligo Synthesis

GenScript provides comprehensive RNA backbones with flexible synthesis scales for your antisense studies.


GenScript provides a wide variety of modifications for your individual research need. The modifications range from

General modifications such as modified bases, phosphorylation, thiolation, linkages, etc.

Labeling such as fluorescent/non-fluorescent dye labeling, dual-labeled and multiple labeling

Backbone modifications such as DNA containing thiophosphodiester linkages.


GenScript's RNase-Free HPLC purification is carefully performed in an RNase-free environment. Reagents, equipment and processing are all constantly monitored for RNase contamination.

Additional Service

Extra $0.20/tube for aliquoting into over 5 tubes.

Services Details

Quotations and Ordering

For quotations, please use our secured Online Quotation/Ordering system. However, you may also contact us by email, phone (1-732-885-9188) or fax (1-732-210-0262).

Orders can be placed directly through our secured Online Quotation/Ordering system with a formal PO (Purchase Order) or credit card.

For batch orders, please download and complete our Quick Quotation Request and send it to us via email or fax.

Our customer service representatives are available 24 hours Monday through Friday. You may contact us anytime for assistance.


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