Overview

VHH is a promising tool in therapeutics and immunodiagnostics applications, such as developing recombinant antibody drugs and CAR-T therapy. GenScript has developed a series of rabbit monoclonal (MonoRab™) anti-VHH antibodies to facilitate your research of VHHs.

Read More about VHHs.

Features

MonoRab technology guarantees high affinity: Kd ≈ 10-11 M

MonoRab™ technology guarantees high affinity: Kd ≈ 10-11 M

No cross reactivity with other species

No cross reactivity with other species

Specific to camelid IgG2 & IgG3

Specific to camelid IgG2 & IgG3

Recognize conformational epitopes of the VHH domain

Recognize conformational epitopes of the VHH domain

Recognize both camelid and humanized VHHs

Recognize both camelid and humanized VHHs

Product List

Selection Guide

Product
Type
Species
Specificity
Unconjugated Conjugated
HRP Biotin iFluor
488
iFluor
555
iFluor
647
PE FITC
Anti-Camelid VHH,
mAb
Llama, Camel,
Alpaca
A01860 A01861 A01995 A01862 A01863 A01994
Anti-Humanized VHH,
mAb
Humanized, Llama,
Camel, Alpaca
A02165 A02167 A02166 A02168 A02169 A02170
Anti-Camelid VHH,
mAb Cocktail
Llama, Camel,
Alpaca
A02014 A02016 A02015 A02021 A02020 A02019 A02018 A02017

Applications

Related Products

Cat. No. Product Name Quantity Price Order
A02022
MonoRab™ Rabbit IgG Control (Whole Molecule), mAb
$110.00 200 μl
 
A02025
MonoRab™ Rabbit IgG Control [PE] (Whole Molecule), mAb
$110.00 200 μl
 
A02026
MonoRab™ Rabbit IgG Control [iFluor 647] (Whole Molecule), mAb
$110.00 200 μl
 
A02027
MonoRab™ Rabbit IgG Control [iFluor 555] (Whole Molecule), mAb
$110.00 200 μl
 
A02028
MonoRab™ Rabbit IgG Control [iFluor 488] (Whole Molecule), mAb
$110.00 200 μl
 
L00905
MonoRab™ Anti-Camelid VHH Affinity Resin
$474.99
 

Resource

MonoRab™ Anti-Camelid VHH Antibodies
MonoRab™ Anti-VHH Antibodies

Unique Tools for Detecting Camelid/Humanized Single Domain Antibodies

Free Download

What is VHH?

Members of the Camelidae family including llamas, alpacas, and camels produce two different types of IgG antibodies. One type is the conventional IgG1 (MW~150 kDa) composed of two heavy chains and two light chains. The other type includes IgG2 and IgG3 (MW~90 kDa) which lack the light chains as well as one constant domain of the heavy chain (CH1 domain). Those antibodies are commonly called heavy chain antibodies (HCAbs). The variable domain of the HCAbs is referred to as single domain antibody, also called sdAb or VHH. VHH is considered the smallest antigen-binding entity.

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