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Downstream Immunoassay Development Service
An anti-idiotype antibody (anti-ID Ab, see the schematic diagram) binds to the idiotype of another antibody, usually an antibody drug. An idiotype can be defined as the specific combination of idiotopes present within an antibodies complement determining regions. Since anti-ID Abs are capable of binding to antibody drugs within biological fluids, they are commonly used in preclinical setting for antibody drug pharmacokinetics (PK) and pharmacodynamics (PD). Due to the similarity between anti-ID Abs and anti-drug antibodies, anti-ID Abs are also commonly used as a reference standard for antibody drug immunogenicity(immune response, IR) studies.
GenScript has 14 years experience in developing of highly sensitive and specific polyclonal and monoclonal anti-ID Abs to support your antibody drug development. We try to work as closely as possible with our customers to understand their specific downstream application in order to generate their perfect anti-ID. See our case studies
Provide GenScript with a Case Study Highlighting Our Custom Antibodies in Your Experiment to Receive 15% Off Of Your Next Custom Antibody Order
Perfect for picomolar-level immunoassay sensitivity
Perfect for ELISA kit development
Sequence delivery & gram level recombinant Ab supply
* : At least one pairing anti-ID Ab (any kind) is guaranteed to delivery Note: Complex-specific anti-ID Ab need to be further inquired
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