Upgraded! Anti-idiotype Antibody Services
An anti-idiotype antibody (anti-ID Ab, see the schematic diagram) binds to the idiotype of another antibody, usually an antibody drug. An idiotype can be defined as the specific combination of idiotopes present within an antibodies complement determining regions. Since anti-ID Abs are capable of binding to antibody drugs within biological fluids, they are commonly used in preclinical setting for antibody drug pharmacokinetics (PK) and pharmacodynamics (PD). Due to the similarity between anti-ID Abs and anti-drug antibodies, anti-ID Abs are also commonly used as a reference standard for antibody drug immunogenicity, anti-drug antibody (ADA) studies.
GenScript has 14 years experience in developing of highly sensitive and specific polyclonal and monoclonal anti-ID Abs to support your antibody drug development. We try to work as closely as possible with our customers to understand their specific downstream application in order to generate their perfect anti-ID. See our case studies »
We also offer ready-made anti-idiotype antibody products. Learn More »
Anti-Idiotype Antibodies
| Type | 1. Antigen-blocking | 2. Non-blocking | 3. Complex-specific |
|---|---|---|---|
| Schematic diagram |  |
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| Feature | Paratope-specific | Not Paratope-specific | Partially paratope-specific |
| Antigen binding | Inhibitory | Not inhibitory | Not inhibitory |
| Application | Detect free drug only | Detect total drug (free and bound) | Detect bound drug typically |
| Selection Guideline |
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Features of GenScript Anti-ID Antibodies Service
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Application tailored anti-id mAb
Fit for capture ELISA & sandwich ELISA
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Fast delivery
8 weeks to delivery purified Anti-id pAb with guaranteed quantity
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High success rate
100% for blocking anti-id Ab
Anti-ID Package Details
| Typical Application | Starting material | Turnaround time (weeks) | Deliverable | Price |
|---|---|---|---|---|
Positive control for ADA mensuration |
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QC standard: ELISA titer ≥ 1: 243,000; cross rate ≤ 2% |
15% off for 10 mg 25% off for 15 mg 30% off for 20 mg |
#Other type: including but not limited to peptide, protein, ADC, SvFv & bispecific antibody.
| Typical application | Starting material | Turnaround time (weeks) | Deliverable | Price |
|---|---|---|---|---|
PK and neutralization Ab analysis |
|
21-27 |
QC standard: ELISA titer ≥ 1: 243,000 |
Get a Quotation |
Guarantee to deliver one type of anti-id mAb (blocking or non-blocking)
| Typical application | Starting material | Turnaround time (weeks) | Deliverable | Price |
|---|---|---|---|---|
PK and neutralization Ab analysis |
|
21-29 |
QC standard: ELISA titer ≥1: 243,000 |
Get a Quotation |
Guarantee to deliver two types of anti-id mAb (blocking & non-blocking)
Guarantee to deliver at least one anti-id mAb pair
Quotation and Ordering
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