The role of LC-MS in antibody drug discovery
There are many analytical methods developed for antibody characterization, including various HPLC methods, analytical ultracentrifugation, MS, DSC and others. Among these techniques, Liquid Chromatography combined with Mass Spectrometry (LC-MS) is a proven analytical technique of choice, used in the various stages of antibody drug discovery and development. But what exactly is LC-MS and why is it so popular? In this webinar, we will review the basics of LC-MS and take a closer look at the analysis capabilities of this versatile technique. We will review how the LC-MS platform at GenScript allows our scientists to develop a deeper understanding of the Antibody drug structure, including disulfide linkages, post-translational modifications, N-linked glycans and more. We will also look at strategies for optimizing the use of this technique, along with potential pitfalls and solutions.
|The role of LC-MS in Antibody Drug Discovery|
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