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MELK Antibody, pAb, Rabbit

Synonyms Rabbit Anti-MELK pAb;
Description MELK (Maternal Embryonic Leucine zipper Kinase, Protein kinase PK38) is one member of the Snf1/AMPK related kinase family of serine/threonine kinases. MELK kinase contains an N-terminal serine/threonine kinase domain that includes all 12 typical catalytic subdomains, and a KA1 (kinase-associated) domain. It is implicated in stem cell renewal, cell cycle progression, and pre-m-RNA splicing. The kinase is also a marker for self-renewing multipotent neural progenitors in the developing forebrain. MERK phosphorylates zinc finger protein 622 (ZNF622) and may contribute to its redirection to the nucleus. MERK may be involved in the inhibition of spliceosome assembly during mitosis.

GenScript Rabbit Anti-MELK Polyclonal Antibody is developed in rabbit using a KLH-coupled synthetic peptide from C-terminal of human MELK. (Swiss Prot: Q14680).
Host Species Rabbit
Antigen Species Human
Conjugation Unconjugated
Immunogen KLH-coupled synthetic peptide from C-terminal of human MELK (Swiss Prot: Q14680).
Purification Immunoaffinity chromatography

Subclass Rabbit IgG
Concentration 0.5 mg/ml, lyophilized with PBS, pH 7.4, containing 0.02% sodium azide
Reconstitution Reconstitute the lyophilized powder with deionized water (or equivalent) to an antibody concentration of 0.5 mg/ml.
Specificity GenScript Rabbit Anti-MELK Polyclonal Antibody detects endogenous levels of human and mouse MELK protein.
Species Reactivity Human and mouse. This product has not been tested with other species yet.
Storage The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles.

MELK Antibody, PAb, Rabbit
MELK Antibody, PAb, Rabbit

Western blot analysis of cell lysates using 1 µg/ml Rabbit Anti-MELK Polyclonal Antibody (GenScript, A01390)
The signal was developed with IRDyeTM 800 Conjugated Goat Anti-Rabbit IgG.
Predicted Size: 75 KD
Observed Size: 70 KD

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Cat. No. A01390
40 ug $99.00
100 ug $199.00