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Catalog Products » Other Products » Caspr2 Antibody, pAb, Rabbit

Caspr2 Antibody, pAb, Rabbit

Caspr2 Antibody, PAb, Rabbit

Western blot analysis of tissue lysates using 1 µg/ml Rabbit Anti-Caspr2 Polyclonal Antibody (GenScript, A01426)
The signal was developed with IRDyeTM 800 Conjugated Goat Anti-Rabbit IgG.
Predicted Size: 148 KD
Observed Size: 148 KD

Caspr2 Antibody, PAb, Rabbit

Immunohistochemistry analysis of human brain, cortex tissue slide (Paraffin embedded) using Caspr2 Antibody, pAb, Rabbit (GenScript, Cat.No. A01426, 10 µg/ml)

Synonyms Contacting-associated protein 2 antibody;
Description Contacting-associated protein 2 (Caspr2) is a member of the neurexin superfamily that mediates nervous system cell-cell interactions. The C-terminal region of Caspr2 participates in the association with Kv1.1, Kv1.2 and their Kv-beta-2 subunit. Expression of Caspr2 is regulated directly by transcription factor FOXP2. Disruption or decreased expression of Caspr2 probably leads to a disturbed distribution of potassium channels in the nervous system. Mutations in the Caspr2 gene have been linked to many diseases such as focal epilepsy, autism spectrum disorder and cortical dysplasia-focal epilepsy syndrome (CDFES).

GenScript Rabbit Anti-Caspr2 Polyclonal Antibody is developed in rabbit using a KLH-coupled synthetic peptide from C-terminal of human Caspr2 (Swiss Prot: Q9UHC6).
Host Species Rabbit
Antigen Species Human
Conjugation Unconjugated
Immunogen KLH-coupled synthetic peptide from C-terminal of human Caspr2 (Swiss Prot: Q9UHC6)
Purification Immunoaffinity chromatography

Subclass Rabbit IgG
Concentration 0.5 mg/ml, lyophilized with PBS, pH 7.4, containing 0.02% sodium azide.
Reconstitution Reconstitute the lyophilized powder with deionized water (or equivalent) to an antibody concentration of 0.5 mg/ml.
Specificity GenScript Rabbit Anti-Caspr2 Polyclonal Antibody detects endogenous levels of mouse and rat Caspr2. It is predicted to react with human Caspr2 according to sequence homology.
Positive Control: mouse brain and rat brain.
Species Reactivity Mouse and rat. This product has not been tested for other species yet.
Storage The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles.

Working concentrations for specific applications should be determined by the investigator. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Western blot: 0.5-1 µg/ml
Immunohistochemistry: 5-10 µg/ml
Other Applications: user-optimized

  • Caspr2 Antibody, PAb, Rabbit
  • Caspr2 Antibody, PAb, Rabbit

    Western blot analysis of tissue lysates using 1 µg/ml Rabbit Anti-Caspr2 Polyclonal Antibody (GenScript, A01426)
    The signal was developed with IRDyeTM 800 Conjugated Goat Anti-Rabbit IgG.
    Predicted Size: 148 KD
    Observed Size: 148 KD

  • Caspr2 Antibody, PAb, Rabbit
  • Caspr2 Antibody, PAb, Rabbit

    Immunohistochemistry analysis of human brain, cortex tissue slide (Paraffin embedded) using Caspr2 Antibody, pAb, Rabbit (GenScript, Cat.No. A01426, 10 µg/ml)




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Cat. No. A01426
Size
Price
40 ug $99.00
100 ug $199.00