|Synonyms||SAP90 antibody ; Postsynaptic density protein 95 antibody|
|Description||PSD95 (Postsynaptic Density protein 95) is one member of the membrane-associated guanylate kinase (MAGUK) family. PSD95 participates in the assembly of the postsynaptic density complex and is involved in synaptic targeting of AMPA receptors. It interacts with the cytoplasmic tail of NMDA receptor subunits and shaker-type potassium channels. And PSD95 is required for synaptic plasticity associated with NMDA receptor signaling. GenScript Rabbit Anti-PSD95 Polyclonal Antibody is developed in rabbit using a KLH-coupled synthetic peptide within residues 450~500 of human PSD95 (Swiss Prot: P78352).|
|Immunogen||KLH-coupled synthetic peptide within residues 450~500 of human PSD95 (Swiss Prot: P78352).|
|Concentration||0.5 mg/ml, lyophilized with PBS, pH 7.4, containing 0.02% sodium azide.|
|Reconstitution||Reconstitute the lyophilized powder with deionized water (or equivalent) to an antibody concentration of 0.5 mg/ml.|
|Specificity||GenScript Rabbit Anti-PSD95 Polyclonal Antibody detects endogenous levels of rat and mouse PSD95. Predicted to react with human PSD95 according to sequence homology.|
|Species Reactivity||Mouse and rat|
|Predicted Band Size||95 KD|
|Observed Band Size||90 KD|
|Storage||The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles.|
|Working concentrations for specific applications should be determined by the investigator. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Western blot: 0.5-1 µg/ml.
Other Applications: user optimized.
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