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Catalog Products » Antibodies » Primary Antibodies » Phospho-Specific Antibodies » IL-6 Antibody, mAb, Mouse

IL-6 Antibody, mAb, Mouse

Synonyms BSF2 Antibody,mAb,Mouse; CDF Antibody,mAb,Mouse
Description Interleukin 6 (IL6) is a multifunctional 24 kDa protein originally discovered in the medium of RNA stimulated fibroblastoid cells. It is upregulated by IL1, TNF, PDGF, IFN beta, TNF alpha, NGF, IL17 and downregulated by glucocorticoids IL4 and TGF beta. IL6 appears to be directly involved in the responses that occur after infection and cellular injury, and it may prove to be as important as IL1 and TNF alpha in regulating the acute phase response. IL6 has also been implicated in regulating adipose mass.
IL6 is reported to be produced by fibroblasts, activated T cells, activated monocytes or macrophages, and endothelial cells. It acts upon a variety of cells including fibroblasts, myeloid progenitor cells, T cells, B cells, and hepatocytes. In addition, IL6 appears to interact with IL2 in the proliferation of T lymphocytes. IL6 potentiates the proliferative effect of IL3 on multipotential hematopoietic progenitors.
Host Species Mouse
Antigen Species Human
Conjugation Unconjugated
Immunogen Human IL-6 recombinant protein
Fusion Partner Spleen cells were fused with SP2/0-Ag14 mouse myeloma cells
Purification Protein A affinity column

Subclass Mouse IgG2b, κ
Clone ID 2F6H6
Concentration 0.5 mg/ml, lyophilized with PBS, pH 7.4, containing 0.02% sodium azide
Reconstitution Reconstitute the lyophilized powder with deionized water (or equivalent) to an final concentration of 0.5 mg/ml.
Specificity No cross reactivity with IL-1α, IL-1β, IL-4, IL-8, IL-18
Storage The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles.


IL-6 Antibody, MAb, Mouse
IL-6 Antibody, MAb, Mouse

Cross reactivity detection




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Cat. No. A01517
Size
Price
40 ug $99.00
100 ug $199.00
 
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