|Synonyms||Neuraminidase of Influenza A Virus Antibody;|
|Description||Influenza A (H1N1) virus is a subtype of influenzavirus A and the most common cause of influenza (flu) in humans. A strain of swine-origin H1N1 was responsible for the 2009 flu pandemic. Neuraminidase (NA), a single-pass type II membrane homotetramer, is a major membrane glycoproteins found on the surface of influenza virus. It cleaves the hemagglutinin HA-sialic acid bondage from the newly formed virions and the host cell receptors during budding. Therefore, NA is described as a receptor-destroying enzyme which facilitates virus release and efficient spread of the progeny virus from cell to cell.
GenScript H1N1 NA Antibody is developed in rabbit using a KLH-coupled synthetic peptide within residues 400-450 of Influenza A (H1N1) 2009 virus NA protein (GenBank: CY040001).
|Antigen Species||Influenza A|
|Immunogen||KLH-coupled synthetic peptide within residues 400-450 of Influenza A (H1N1) 2009 virus NA protein (GenBank: CY040001)|
|Concentration||0.5 mg/ml, lyophilized with PBS, pH 7.4, containing 0.02% sodium azide|
|Reconstitution||Reconstitute the lyophilized powder with deionized water (or equivalent) to an antibody concentration of 0.5 mg/ml.|
|Specificity||GenScript H1N1 NA Antibody detects influenza A (H1N1) NA protein.|
|Species Reactivity||Influenza A virus (H1N1)|
|Predicted Band Size||53 KD|
|Observed Band Size||53 KD|
|Storage||The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles.|
|Working concentrations for specific applications should be determined by the investigator. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Western blot: 0.5-1 µg/ml
Other Applications: user optimized
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