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Catalog Products » Antibodies » Primary Antibodies » BRCA2 antibody, pAb, Rabbit

BRCA2 antibody, pAb, Rabbit

Synonyms FACD antibody;
Description Breast cancer type 2 susceptibility protein (BRCA2) is involved in double-strand break repair and/or homologous recombination. It may participate in S phase checkpoint activation. In addition, It interacts with RAD51 and DSS1 and binds to ubiquitinated FANCD2. It also interacts with PALB2, enabling the recombinational repair and checkpoints functions. Defects in BRCA2 can cause genetic susceptibility to breast cancer (BC), also called susceptibility to familial breast-ovarian cancer type 2 (BROVCA2).
GenScript BRCA2 Antibody is developed in rabbit using a KLH-coupled synthetic peptide within residues 2480–2530 of human BRCA2 (Swiss Prot: P51587).
Host Species Rabbit
Antigen Species Human
Conjugation Unconjugated
Immunogen KLH-coupled synthetic peptide within residues 2480–2530 of human BRCA2 (Swiss Prot: P51587)
Purification Immunoaffinity chromatography.

Subclass Rabbit IgG
Concentration 0.5 mg/ml, lyophilized with PBS, pH 7.4, containing 0.02% sodium azide.
Reconstitution Reconstitute the lyophilized powder with deionized water (or equivalent) to an antibody concentration of 0.5 mg/ml.
Specificity GenScript BRCA2 Antibody detects endogenous levels of human and mouse BRCA2.
Positive Control: HEK293 and Mouse brain
Species Reactivity Mouse
Predicted Band Size 390 KD
Observed Band Size 390 KD
Storage The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles.

Working concentrations for specific applications should be determined by the investigator. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Western blot: 0.5-1 µg/ml
Flow cytometry: 1-3 µg for 1 x 106 cells
Other applications: user optimized

  • BRCA2 Antibody, PAb, Rabbit
  • BRCA2 Antibody, PAb, Rabbit

    Flow cytometric analysis of HEK293 cells using BRCA2 antibody, pAb, Rabbit (GenScript, A01594; shaded histogram)
    or with an isotype control antibody (GenScript, A01008; open histogram), followed by R-PE conjugated anti-rabbit IgG.




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Cat. No. A01594
Size Price
40 ug $99.00