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Catalog Products » Other Products » New Products » Dysbindin antibody, pAb, Rabbit

Dysbindin antibody, pAb, Rabbit

Dysbindin Antibody, PAb, Rabbit

Western blot analysis of cell lysates using Dysbindin Antibody, pAb, Rabbit (GenScript, A01619, 1 µg/ml)
The signal was developed with IRDye™ 800 Conjugated Goat Anti-Rabbit IgG.
Predicted Size: 39 KD
Observed Size: 55 KD

Dysbindin Antibody, PAb, Rabbit

Immunohistochemistry analysis of human tonsil tissue slide (Paraffin embedded) using Dysbindin antibody, pAb, Rabbit (GenScript, Cat.No. A01619, 10 µg/ml)

Synonyms DTNBP1 antibody, pAb, Rabbit;
Description Dysbindin, also known as dystrobrevin-binding protein 1 that contains acoiled-coil. Dysbindin upregulates expression of the pre-synaptic proteins SNAP25 and synapsin I, thereby increasing glutamate release and promoting neuronal viability through Akt signaling. It is a component of the biogenesis of lysosome-related organelles complex-1 (BLOC1), which regulates trafficking to lysosome-related organelles and includes the proteins pallidin, muted, and cappuccino. Dysbindin also binds to alpha- and beta-dystrobrevins, components of the dystrophin-associated protein complex.
GenScript Dysbindin Antibody, pAb, Rabbit is developed in rabbit using a KLH-coupled synthetic peptide within residues 120–170 of human Dysbindin (Swiss Prot: Q96EV8).
Host Species Rabbit
Antigen Species Human
Conjugation Unconjugated
Immunogen KLH-coupled synthetic peptide within residues 120–170 of human Dysbindin (Swiss Prot: Q96EV8)
Purification Immunoaffinity chromatography

Subclass Rabbit IgG
Concentration 0.5 mg/ml, lyophilized with PBS, pH 7.4, containing 0.02% sodium azide
Reconstitution Reconstitute the lyophilized powder with deionized water (or equivalent) to an antibody concentration of 0.5 mg/ml.
Specificity GenScript Dysbindin Antibody, pAb, Rabbit detects endogenous levels of human Dysbindin.
Positive Control: U251
Species Reactivity Human. This product has not been tested with other species yet.
Predicted Band Size 39 KD
Observed Band Size 55 KD
Storage The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below. Avoid repeated freezing and thawing cycles.

Working concentrations for specific applications should be determined by the investigator. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Western blot: 0.5-1 µg/ml
Immunohistochemistry: 5-10 µg/ml
Other Applications: User optimized
Technical Manual ELISA Protocol(pdf)
Western Blot Protocol(pdf)
FACS Protocol(pdf)
IHC Protocol(pdf)
IP Protocol(pdf)

Dysbindin Antibody, PAb, Rabbit
Dysbindin Antibody, PAb, Rabbit

Western blot analysis of cell lysates using Dysbindin Antibody, pAb, Rabbit (GenScript, A01619, 1 µg/ml)
The signal was developed with IRDye™ 800 Conjugated Goat Anti-Rabbit IgG.
Predicted Size: 39 KD
Observed Size: 55 KD

Dysbindin Antibody, PAb, Rabbit
Dysbindin Antibody, PAb, Rabbit

Immunohistochemistry analysis of human tonsil tissue slide (Paraffin embedded) using Dysbindin antibody, pAb, Rabbit (GenScript, Cat.No. A01619, 10 µg/ml)




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Cat. No. A01619
Size
Price
40 ug $99.00
 
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