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Home » Gene Synthesis & Molecular Biology Services » Human PLA2R1 Antibody (6E8), mAb, Mouse

Human PLA2R1 Antibody (6E8), mAb, Mouse

Human PLA2R1 Antibody (6E8), MAb, Mouse

ELISA binding of Human PLA2R1 Antibody (6E8) (GenScript, A01888-40) with Human PLA2R1 recombinant protein.
Coating antigen: PLA2R1, 1 µg/ml.
PLA2R1 antibody dilutions start from 1000 ng/ml, EC50= 53.12 ng/ml.

Human PLA2R1 Antibody (6E8), MAb, Mouse

Western Blot validation of Human PLA2R1 Antibody (6E8) (GenScript, A01888-40) with Human PLA2R1 recombinant protein.
Lane 1: 50 ng Human PLA2R1 recombinant protein
Lane 2: 25 ng Human PLA2R1 recombinant protein
Lane 3: 10 ng Human PLA2R1 recombinant protein
Primary Antibody:
Human PLA2R1 Antibody (6E8) (GenScript, A01888-40) 1 μg/ml
Secondary Antibody:
Goat anti-Mouse IgG (H&L) [IRDye⁸⁰⁰] (Licor,926-32211)0.125 μg/ml

Synonyms Mouse monoclonal to 180 kDa secretory phospholipase A2 receptor, C-type lectin domain family 13 member C, CLEC13C, M-type receptor, phospholipase A2 receptor 1, phospholipase A2 receptor 1, 180kD, phospholipase A2 receptor 1, 180kDa, PLA2-R, PLA2G1R, PLA2IR, PLA2R, PLA2R1, Secretory phospholipase A2 receptor
Description PLA2R1 (Phospholipase A2 Receptor 1) is a protein coding gene. The encoded protein likely exists as both a transmembrane form and a soluble form. The transmembrane receptor may play a role in clearance of phospholipase A2, thereby inhibiting its action. The soluble secretory phospholipase A2 receptor form is circulating and acts as a negative regulator of sPLA2 (secretory phospholipase A2) functions by blocking the biological functions of sPLA2-IB/PLA2G1B. Diseases associated with PLA2R1 include Membranoproliferative Glomerulonephritis and Membranous Nephropathy. Among its related pathways are metabolism and acyl chain remodeling of PE (phosphatidylethanolamine). Alternatively spliced transcript variants encoding different isoforms have been identified.
Host Species Mouse
Conjugation Unconjugated
Immunogen Recombinant Human PLA2R1
Purification Protein A affinity column

Subclass IgG1,κ
Clone ID 6E8
Concentration 0.5 mg/ml, lyophilized with PBS, pH 7.4, containing 0.02% sodium azide. (It may be customized for bulk orders.)
Reconstitution Reconstitute the lyophilized antibody with deionized water (or equivalent) to a final concentration of 0.5 mg/ml.
Specificity The product is specific for human PLA2R1. This antibody binds with recombinant PLA2R1 protein in ELISA and western blot.
Storage The lyophilized product remains stable up to 1 year at -20 °C from date of receipt. Upon reconstitution, it can be stored for 2-3 weeks at 2-8 °C or for up to 12 months at -20 °C or below. Avoid repeated freezing and thawing cycles.
Note GenScript can customize this product per customer's request including product size, buffer components, etc.

Working concentrations for specific applications should be determined by the investigators. The appropriate concentration may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
ELISA detection: 0.05-0.5 µg/ml
Western blot: 1 µg/ml
Other applications: user-optimized

  • Human PLA2R1 Antibody (6E8), MAb, Mouse
  • Human PLA2R1 Antibody (6E8), MAb, Mouse

    ELISA binding of Human PLA2R1 Antibody (6E8) (GenScript, A01888-40) with Human PLA2R1 recombinant protein.
    Coating antigen: PLA2R1, 1 µg/ml.
    PLA2R1 antibody dilutions start from 1000 ng/ml, EC50= 53.12 ng/ml.

  • Human PLA2R1 Antibody (6E8), MAb, Mouse
  • Human PLA2R1 Antibody (6E8), MAb, Mouse

    Western Blot validation of Human PLA2R1 Antibody (6E8) (GenScript, A01888-40) with Human PLA2R1 recombinant protein.
    Lane 1: 50 ng Human PLA2R1 recombinant protein
    Lane 2: 25 ng Human PLA2R1 recombinant protein
    Lane 3: 10 ng Human PLA2R1 recombinant protein
    Primary Antibody:
    Human PLA2R1 Antibody (6E8) (GenScript, A01888-40) 1 μg/ml
    Secondary Antibody:
    Goat anti-Mouse IgG (H&L) [IRDye⁸⁰⁰] (Licor,926-32211)0.125 μg/ml




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Cat. No. A01888
Size
Price
40 µg $99.00