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Catalog Products » Antibodies » MonoRab® Rabbit Monoclonal Antibody Product » MonoRabᵀᴹ Anti-Rituximab Antibody (194D7)[Biotin], mAb, Rabbit

MonoRabᵀᴹ Anti-Rituximab Antibody (194D7)[Biotin], mAb, Rabbit

MonoRabᵀᴹ Anti-Rituximab Antibody (194D7)[Biotin], MAb, Rabbit

Anti-Rituximab Antibody (194D7) [Biotin], mAb, Rabbit (GenScript, A01944-40) binds with Rituximab. While the antibody does not recognize the human IgG Fc fragment (data not shown).
Coating antigen: Rituximab, 1 µg/ml.
Anti-Rituximab Antibody (194D7) [Biotin] (GenScript, A01944-40) dilution start from 1,000 ng/ml. EC₅₀= 2.889 ng/ml.

MonoRabᵀᴹ Anti-Rituximab Antibody (194D7)[Biotin], MAb, Rabbit

Standard curve of Rituximab Sandwich ELISA. The Rituximab Sandwich ELISA assay is developed by using Anti-Rituximab Antibody (137C6), mAb, Rabbit (GenScript, A01942-40) and Anti-Rituximab Antibody (194D7) [Biotin], mAb, Rabbit (GenScript, A01944-40) as capture and detection antibody, respectively.
The sensitivity of detecting Rituximab is about 30 pg/ml.

Description Rituximab was approved for medical use in 1997. It is on the World Health Organization's List of Essential Medicines, the most effective and safe medicines needed in a health system. Rituximab, sold under the brand name Rituxan among others, is a medication used to treat certain autoimmune diseases and types of cancer. It is used for non-Hodgkin's lymphoma, chronic lymphocytic leukemia, rheumatoid arthritis, idiopathic thrombocytopenic purpura, pemphigus vulgaris and myasthenia gravis. Rituximab is a chimeric monoclonal antibody against the protein CD20, which is primarily found on the surface of immune system B cells. When it binds to this protein it triggers cell death.
Host Species Rabbit
Conjugation Biotin
Immunogen Rituximab
Purification Protein A affinity column

Subclass IgG1
Clone ID 194D7
Concentration 0.5 mg/ml, lyophilized with PBS, pH 7.4, contains 1% BSA and 0.02% sodium azide. (Might be eligible for customized bulk orders.)
Reconstitution Reconstitute the lyophilized antibody with deionized water (or equivalent) to a final concentration of 0.5 mg/ml.
Specificity The product is specific for Rituximab. The antibody is recommended as a detection antibody in a pharmacokinetic (PK) bridging assay with capture antibody GenScript, A01942-40, MonoRabᵀᴹ Anti-Rituximab Antibody (137C6), mAb, Rabbit.
Storage The lyophilized product remains stable up to 1 year at -20 °C from date of receipt. Upon reconstitution, it can be stored for 2-3 weeks at 2-8 °C or for up to 12 months at -20 °C or below. Avoid freeze/thaw cycles.
Note GenScript can customize this product per customer's request including product size, buffer components, etc.

Working concentrations for specific applications should be determined by the investigators. The appropriate concentration may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.

ELISA detection: 0.005-1 µg/ml
Other applications: user-optimized

  • MonoRabᵀᴹ Anti-Rituximab Antibody (194D7)[Biotin], MAb, Rabbit
  • MonoRabᵀᴹ Anti-Rituximab Antibody (194D7)[Biotin], MAb, Rabbit

    Anti-Rituximab Antibody (194D7) [Biotin], mAb, Rabbit (GenScript, A01944-40) binds with Rituximab. While the antibody does not recognize the human IgG Fc fragment (data not shown).
    Coating antigen: Rituximab, 1 µg/ml.
    Anti-Rituximab Antibody (194D7) [Biotin] (GenScript, A01944-40) dilution start from 1,000 ng/ml. EC₅₀= 2.889 ng/ml.

  • MonoRabᵀᴹ Anti-Rituximab Antibody (194D7)[Biotin], MAb, Rabbit
  • MonoRabᵀᴹ Anti-Rituximab Antibody (194D7)[Biotin], MAb, Rabbit

    Standard curve of Rituximab Sandwich ELISA. The Rituximab Sandwich ELISA assay is developed by using Anti-Rituximab Antibody (137C6), mAb, Rabbit (GenScript, A01942-40) and Anti-Rituximab Antibody (194D7) [Biotin], mAb, Rabbit (GenScript, A01944-40) as capture and detection antibody, respectively.
    The sensitivity of detecting Rituximab is about 30 pg/ml.


Cat. No.
Product Name
Price
A01942-40
MonoRabᵀᴹ Anti-Rituximab Antibody (137C6), mAb, Rabbit - 40 µg
$198.00
A01943-40
MonoRabᵀᴹ Anti-Rituximab Antibody (194D7), mAb, Rabbit - 40 µg
$198.00
 


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Cat. No. A01944
Size
Price
40 µg $198.00