Catalog Products » Antibodies » Primary Antibodies » Immune Checkpoint Antibodies » Human HVEM Antibody (10C6), mAb, Mouse

Human HVEM Antibody (10C6), mAb, Mouse

*This product has been discontinued!*
The product is specific for human HVEM
A01959
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Overview
Specificity The product is specific for human HVEM
Host Species Mouse
Immunogen Recombinant HVEM protein
Conjugate Unconjugated

Applications
Working concentrations for specific applications should be determined by the investigators. The appropriate concentration may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Application Recommended Usage
ELISA 0.01-0.05 µg/ml
Flow Cytometry 1- 5 µg/ml

Properties
Form Lyophilized
Storage Buffer lyophilized with PBS, pH 7.4, containing 0.02% sodium azide.
Reconstitution Reconstitute the lyophilized powder with deionized water (or equivalent) to an final concentration of 0.5 mg/mL.
Storage Instructions The lyophilized product remains stable up to 1 year at -20 °C from date of receipt. Upon reconstitution, it can be stored for 2-3 weeks at 2-8 °C or for up to 12 months at -20 °C or below. Avoid repeated freezing and thawing cycles.
Purification Protein A affinity column
Isotype Mouse IgG1
Clonality Monoclonal
Clone ID 10C6
Note GenScript can customize this product per customer's request including product size, buffer components, etc.

Background
Target Background HVEM, also known as CD270, is a type 1 transmembrane protein. It is a member of the TNFR superfamily with a molecular weight of 30kDa. HVEM is expressed on hematopoietic cells such as T cells, B cells, dendritic cells, monocytes, neutrophils and NK cells. It participates in regulating lymphocyte activation and homeostasis in immune responses. HVEM activates NF-kB through the TNF-related cytokine LIGHT during T cell activation.
Synonyms Mouse monoclonal to Human TNFRSF14/ATAR/CD270/LIGHTR/TR2

For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.


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