Catalog Products » Antibodies » Primary Antibodies » MonoRab™ SARS-CoV-2 Neutralizing Antibody (BS-R2B17), mAb, Rabbit
MonoRab™ SARS-CoV-2 Neutralizing Antibody (BS-R2B17), MAb, Rabbit

ELISA binding of MonoRabTM SARS-CoV-2 Neutralizing Antibody (BS-R2B17), mAb, Rabbit (GenScript, A02052) with recombinant SARS-CoV-2 Spike Protein S1 RBD(GenScript, Z03483) and SARS-CoV RBD .

MonoRab™ SARS-CoV-2 Neutralizing Antibody (BS-R2B17), MAb, Rabbit

MonoRab™ SARS-CoV-2 Neutralizing Antibody (BS-R2B17), mAb, Rabbit (GenScript, A02052) blocks SARS-CoV-2 Omicron RBD binding with Human ACE2 recombinant protein by sVNT.

SARS-CoV-2 S-RBD Omicron/B.1.1.529 (GenScript, Z03728)
MonoRab™ SARS-CoV-2 Neutralizing Antibody (BS-R2B17), mAb, Rabbit dilution start from 10 µg/ml.

MonoRab™ SARS-CoV-2 Neutralizing Antibody (BS-R2B17), MAb, Rabbit

Pseudovirus Neutralization Test of SARS-CoV-2 pseudovirus–hACE2 interaction with MonoRab™ SARS-CoV-2 Neutralizing Antibody (BS-R2B17), mAb, Rabbit (GenScript, A02052).

Control: HEK293/ACE2 cells were infected with SARS-CoV-2 pseudovirus
SARS-CoV-2 Pseudovirus Neutralization Assay kit_Luc reporter (GenScript, SC2087A)
SARS-CoV-2 B.1.617.2 (Delta) Pseudovirus Neutralization Assay kit _Luc reporter (GenScript, SC2087V)
SARS-CoV-2 B.1.1.529 (Omicron) Pseudovirus Neutralization Assay kit _Luc reporter (GenScript, SC2087-027)

MonoRab™ SARS-CoV-2 Neutralizing Antibody (BS-R2B17), mAb, Rabbit (GenScript, A02052) dilutions start from 40 µg/ml.

MonoRab™ SARS-CoV-2 Neutralizing Antibody (BS-R2B17), MAb, Rabbit

Dose-response curve of MonoRab™ SARS-CoV-2 Neutralizing Antibody (BS-R2B17), mAb, Rabbit (GenScript, A02052) on SARS-CoV-2 Multiplex sVNT.

The final concentration of RBD recombinant proteins were 60 ng/mL. MonoRab™ SARS-CoV-2 Neutralizing Antibody (BS-R2B17), mAb, Rabbit (GenScript, A02052) dilutions started from 10 µg/mL.
MonoRab™ SARS-CoV-2 Neutralizing Antibody (BS-R2B17), mAb, Rabbit (GenScript, A02052) can block the binding of SARS-CoV-2 omicron variant XBB sublineage and BQ.1.1 sublineage to Human ACE2.

MonoRab™ SARS-CoV-2 Neutralizing Antibody (BS-R2B17), mAb, Rabbit

The product is specific for SARS-CoV-2 Spike Protein S1 subunit and its RBD domain. The product can recognize and neutralize Wild-Type SARS-CoV-2 and Variants of Concern (VOC) including Alpha, Beta, Delta, and Omicron. Reactivity with Gamma variant has not been tested.
A02052
$375.00

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Overview
Specificity The product is specific for SARS-CoV-2 Spike Protein S1 subunit and its RBD domain.
The product can recognize and neutralize Wild-Type SARS-CoV-2 and Variants of Concern (VOC) including Alpha, Beta, Delta, and Omicron. Reactivity with Gamma variant has not been tested.
Host Species Rabbit
Immunogen Recombinant SARS-CoV-2 Spike protein fragment
Conjugate Unconjugated

Applications
Working concentrations for specific applications should be determined by the investigators. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following concentration ranges are recommended starting points for this product.
Application Recommended Usage
ELISA 0.01-0.1 µg/ml
Flow Cytometry 10 µg/ml
Surrogate Virus Neutralization Test (sVNT) 0.2-1 µg/ml

Properties
Form Liquid
Storage Buffer 0.2 μm filtered solution in PBS, pH 7.4.
Concentration 1 mg/ml
Storage Instructions Store at -20°C. This product is stable for 1 year upon receipt, when handled and stored as instructed. Avoid repeated freezing and thawing cycles.
Purification Protein A affinity column
Isotype Rabbit IgG
Clonality Monoclonal
Clone ID BS-R2B17
Note GenScript can customize this product per customer's request including product size, buffer components, etc.

Examples
  • MonoRab™ SARS-CoV-2 Neutralizing Antibody (BS-R2B17), MAb, Rabbit
  • MonoRab™ SARS-CoV-2 Neutralizing Antibody (BS-R2B17), MAb, Rabbit

    ELISA binding of MonoRabTM SARS-CoV-2 Neutralizing Antibody (BS-R2B17), mAb, Rabbit (GenScript, A02052) with recombinant SARS-CoV-2 Spike Protein S1 RBD(GenScript, Z03483) and SARS-CoV RBD .

  • MonoRab™ SARS-CoV-2 Neutralizing Antibody (BS-R2B17), MAb, Rabbit
  • MonoRab™ SARS-CoV-2 Neutralizing Antibody (BS-R2B17), MAb, Rabbit

    MonoRab™ SARS-CoV-2 Neutralizing Antibody (BS-R2B17), mAb, Rabbit (GenScript, A02052) blocks SARS-CoV-2 Omicron RBD binding with Human ACE2 recombinant protein by sVNT.

    SARS-CoV-2 S-RBD Omicron/B.1.1.529 (GenScript, Z03728)
    MonoRab™ SARS-CoV-2 Neutralizing Antibody (BS-R2B17), mAb, Rabbit dilution start from 10 µg/ml.

  • MonoRab™ SARS-CoV-2 Neutralizing Antibody (BS-R2B17), MAb, Rabbit
  • MonoRab™ SARS-CoV-2 Neutralizing Antibody (BS-R2B17), MAb, Rabbit

    Pseudovirus Neutralization Test of SARS-CoV-2 pseudovirus–hACE2 interaction with MonoRab™ SARS-CoV-2 Neutralizing Antibody (BS-R2B17), mAb, Rabbit (GenScript, A02052).

    Control: HEK293/ACE2 cells were infected with SARS-CoV-2 pseudovirus
    SARS-CoV-2 Pseudovirus Neutralization Assay kit_Luc reporter (GenScript, SC2087A)
    SARS-CoV-2 B.1.617.2 (Delta) Pseudovirus Neutralization Assay kit _Luc reporter (GenScript, SC2087V)
    SARS-CoV-2 B.1.1.529 (Omicron) Pseudovirus Neutralization Assay kit _Luc reporter (GenScript, SC2087-027)

    MonoRab™ SARS-CoV-2 Neutralizing Antibody (BS-R2B17), mAb, Rabbit (GenScript, A02052) dilutions start from 40 µg/ml.

  • MonoRab™ SARS-CoV-2 Neutralizing Antibody (BS-R2B17), MAb, Rabbit
  • MonoRab™ SARS-CoV-2 Neutralizing Antibody (BS-R2B17), MAb, Rabbit

    Dose-response curve of MonoRab™ SARS-CoV-2 Neutralizing Antibody (BS-R2B17), mAb, Rabbit (GenScript, A02052) on SARS-CoV-2 Multiplex sVNT.

    The final concentration of RBD recombinant proteins were 60 ng/mL. MonoRab™ SARS-CoV-2 Neutralizing Antibody (BS-R2B17), mAb, Rabbit (GenScript, A02052) dilutions started from 10 µg/mL.
    MonoRab™ SARS-CoV-2 Neutralizing Antibody (BS-R2B17), mAb, Rabbit (GenScript, A02052) can block the binding of SARS-CoV-2 omicron variant XBB sublineage and BQ.1.1 sublineage to Human ACE2.


Background
Target Background SARS-CoV-2 (Severe acute respiratory syndrome coronavirus 2), also known as 2019-nCoV, is a positive-sense single-stranded RNA virus. It caused coronavirus disease 2019 (COVID-19). SARS-CoV-2 contains glycosylated spike (S) protein, which is composed of S1 subunit and S2 subunit. The S1 contains a receptor-binding domain (RBD) that can bind to ACE2 receptor on target cells.
Synonyms 2019-nCoV Neutralizing Antibody, mAb, Rabbit

For laboratory research use only. Direct human use, including taking orally and injection and clinical use are forbidden.


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