• English
  • Sign In
  • Contact Us
×
Catalog Products » SARS-CoV-2 Neutralizing Antibody Standard

SARS-CoV-2 Neutralizing Antibody Standard

SARS-CoV-2 Neutralizing Antibody Standard

Pseudovirus Neutralization Test of SARS-CoV-2 pseudovirus–hACE2 interaction with SARS-CoV-2 Neutralizing Antibody Standard (GenScript, A02087).
Control: HEK293/ACE2 cells were infected with SARS-CoV-2 pseudovirus.
SARS-CoV-2 Neutralizing Antibody Standard (GenScript, A02087) dilutions start from 40,000 U/ml.
IC₅₀= 853.2 U/ml

SARS-CoV-2 Neutralizing Antibody Standard

Surrogate Virus Neutralization Test (ELISA) of SARS-CoV-2 RBD–hACE2 interaction with SARS-CoV-2 Neutralizing Antibody Standard (GenScript, A02087).
SARS-CoV-2 Neutralizing Antibody Standard (GenScript, A02087) dilutions start from 600 U/ml.
IC50=81.17 U/ml

Synonyms 2019-nCoV Neutralizing Antibody Standard;COVID19 Neutralizing Antibody Standard
Description SARS-CoV-2 (Severe acute respiratory syndrome coronavirus 2), also known as 20SARS-CoV-2 (Severe acute respiratory syndrome coronavirus 2), also known as 2019-nCoV, is a positive-sense single-stranded RNA virus. It caused coronavirus disease in 2019 (COVID-19). SARS-CoV-2 contains glycosylated spike (S) protein, which is composed of S1 subunit and S2 subunit. The S1 contains a receptor-binding domain (RBD) that can bind to ACE2 receptor on target cells.
Neutralizing antibodies against SARS-CoV-2 can block the interaction between SARS-CoV-2 RBD and ACE2. The blocking ability of SARS-CoV-2 neutralizing antibodies is affected by its quantity. This standard product is intended for the calibration of SARS-CoV-2 neutralizing antibodies in the materials or samples. It can be used in the assessment and development of assays for the detection and quantitation of SARS-CoV-2 neutralizing antibodies. The neutralizing antibody standard binds to multiple neutralizing epitopes in the receptor-binding domain. This product has been verified to calibrate the quantitative assay of SARS-CoV-2 neutralizing antibody with the Surrogate Virus Neutralization Test (sVNT) (GenScript, Cat.No L00847-A), plaque reduction neutralization test (PRNT) and pseudovirus neutralization test (pVNT) (GenScript, Cat.No SC2087). Users can design assays to detect and evaluate the quantitation of SARS-CoV-2 neutralizing antibodies by this product.
Formulation The SARS-CoV-2 Neutralizing Antibody Standard supplied in 0.2 μm filtered PBS, pH 7.4. The volume of this standard is 100 μL.

Concentration 1,000,000 U/ml
Unitage The unitage of this product has been defined as an arbitrary unit of 100,000 U.
Stability The unopened product is stable up to the stated expiration date when stored at -20 °C. The opened product is stable for 1 month from the date of opening when stored at 2°C to 8°C.
Storage This standard should be stored at -20 °C upon receipt until use. Avoid repeated freezing and thawing cycles.
Note For Research Use Only. Not for Use in Diagnostic Procedures.

Working concentrations for specific applications should be determined by the researchers. The appropriate concentrations may be affected by secondary antibody affinity, antigen concentration, the sensitivity of the method of detection, temperature, the length of the incubations, and other factors. The suitability of this antibody for applications other than those listed below has not been determined. The following is the recommended concentration range of starting point for this product.
ELISA: 10 U/ml - 1000 U/ml
Pseudovirus Neutralization Test (pVNT): 10 U/ml - 40,000 U/ml
Plaque Reduction Neutralization Test (PRNT): 100 U/ml - 10,000 U/ml
Other applications: user-optimized

  • SARS-CoV-2 Neutralizing Antibody Standard
  • SARS-CoV-2 Neutralizing Antibody Standard

    Pseudovirus Neutralization Test of SARS-CoV-2 pseudovirus–hACE2 interaction with SARS-CoV-2 Neutralizing Antibody Standard (GenScript, A02087).
    Control: HEK293/ACE2 cells were infected with SARS-CoV-2 pseudovirus.
    SARS-CoV-2 Neutralizing Antibody Standard (GenScript, A02087) dilutions start from 40,000 U/ml.
    IC₅₀= 853.2 U/ml

  • SARS-CoV-2 Neutralizing Antibody Standard
  • SARS-CoV-2 Neutralizing Antibody Standard

    Surrogate Virus Neutralization Test (ELISA) of SARS-CoV-2 RBD–hACE2 interaction with SARS-CoV-2 Neutralizing Antibody Standard (GenScript, A02087).
    SARS-CoV-2 Neutralizing Antibody Standard (GenScript, A02087) dilutions start from 600 U/ml.
    IC50=81.17 U/ml




Notice there is no results found, you can visit "Citations Database" for other results.







For more documents, please visit "Technical Support".

Cat. No. A02087
Size Price
20 ul $650.00
100 ul Quote