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The most comprehensive collection for Alzheimer's
Beta-amyloid is a peptide that forms amyloid plaques in the brains of Alzheimer's disease (AD) patients. Beta amyloid peptide consists of 43 amino acids. It is created via the enzymatic digestion of amyloid precursor protein (APP) by beta secretase and gamma secretase. It then forms insoluble fibrous aggregates, causing amyloidosis and neurodegenerative diseases such as AD. Due to beta amyloid's involvement in the pathogenic process of AD, it has become one of the most investigated molecules in AD research projects.
GenScript's FlexPeptide™ peptide synthesis platform allows us to synthesize a comprehensive array of human and rat beta amyloid peptide fragments covering stretches of its amino acid sequence. This can ease the process of elucidating the potential biological interactions of each specific fragment. GenScript's philosophy of continuous improvement and dedication to a cure for AD and other diseases can make us a valuable partner in your mission.
Case study I: β-Amyloid (1-40) Sequence: Asp - Ala - Glu - Phe - Arg - His - Asp -... ... ...- Leu - Met - Val - Gly - Gly - Val - Val Length: 40 aa Purity: 94.80% HPLC results:
MS results:
Case study II: β-Amyloid (1-42), Human Sequence: Asp - Ala - Glu - Phe - Arg - His - Asp -... ... ... - Gly - Gly - Val - Val - Ile - Ala Length: 42 aa Purity: 93.81% HPLC results:
Case study III: β-Amyloid (25-35) Sequence: Gly - Ser - Asn - Lys - Gly - Ala - Ile - Ile - Gly - Leu - Met Length: 11 aa Purity: crude HPLC results:
GenScript offers a wide range of tools, including pan and phospho-specific antibodies and proteins geared toward different areas of neuroscientific research. We have a comprehensive collection of antibodies targeting Parkinson's disease, amyotrophic lateral sclerosis, Huntington's disease and other neurological diseases.
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