Antibodies are indispensable research tools that have enabled researchers across diverse scientific fields to specify, identify, locate and/or quantify their protein targets. As an award-winning custom antibody supplier with over 150,000 antibodies generated to date, GenScript offers a comprehensive antibody production and service portfolio. From antigen design through to custom antibody generation, our expert scientists and talented technical support team have got you covered all the way!
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GenScript is committed to responsible animal care and use. All our antibodies are generated in GenScript's AAALAC and OLAW certified animal facilities (Assurance number: A5892-01, verify at official OLAW website).
Protein identification & quantitation
See how researchers have put GenScript's custom antibodies to use by exploring our citations database!
Dr. Samantha Zaroff, Global Product Manager of Reagent Antibody Services at GenScript, shares the latest insight into MonoRab™, our recently upgraded, expert-developed, rabbit mAb generation platform that yields the most antibody clones for your application.
Learn about antibody generation and the differences between modern antibody production methodsFree Download
Learn all about the extraordinary specificity & affinity of rabbit mAbsFree Download
Learn how polyclonal antibodies maximize your chances of detecting novel target proteinsRead about it here!
A quality antibody is one that bears the appropriate sensitivity and specificity best suited for your target experimental assay. Not all antibodies work across a wide range of applications because each application has different performance specifications. For example, antibodies used in Western blots recognize denatured, linearized protein antigens, while flow cytometry, sandwich ELISA, IF, and functional assays all require antibodies that recognize the natural, folded shape of the protein.
As you begin your quest to generate a custom antibody that is best suited for your research needs, do ask yourself these basic questions:
Being clear on the answers to such questions will ensure that you begin your antibody generation process under optimal conditions, and ultimately maximize your success at generating your desired antibody.
Both polyclonal and monoclonal antibodies have their own advantages and disadvantages, making them useful for different research applications.
Polyclonal antibodies (pAbs) are comprised of a mixed population of antibodies and are therefore capable of recognizing multiple epitopes on any one antigen.
Compared to pAbs, mAbs are more specific because they stem from a single antibody clone and thus recognize a single epitope on an antigen.
Each of these categories has different strengths and weaknesses and it is important to review which type of antigen is most suited for your antibody generation project.