Our anti-SARS-CoV-2 Delta variant Spike S1-RBD mAbs include mouse mAbs, as well as clones that have neutralizing activity and can neutralize ACE2 binding to RBD.
| Clone Name | Isotype | RBD-L452R+E484Q Protein | S1-L452R+E484Q Protein | RBD-L452R Protein | RBD-WT | RBD-E484Q Protein | L452R Protein | L452-WT Peptide | E484Q Peptide | E484-WT Peptide | S-ECD-WT |
|---|---|---|---|---|---|---|---|---|---|---|---|
| L10F10R | IgG2a.K | + | + | + | - | - | - | - | - | - | - |
| L16B9R | IgG1.K | + | + | + | - | - | + | - | - | - | - |
| L18D11R | IgG2a.K | + | + | + | - | - | + | - | - | - | - |
| L20E10R | IgG2a.K | + | + | + | - | - | + | - | - | - | - |
| L7A3R | IgG1.K | + | + | + | - | - | + | - | - | - | - |
| Q2E12P | IgG2a.K | + | + | - | + | - | - | + | - | - | |
| Q6E9P | IgG2a.K | + | + | - | + | - | - | + | - | - | |
| Q8G9P | IgG1.K | + | + | - | + | - | - | + | - | - | |
| Q11F10P | IgG2a.K | + | + | - | + | - | - | + | - | - | |
| Q6C8R | IgG1.K | + | + | - | + | - | - | - | - | - |
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