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Application-guaranteed mAb production
(Western Blot, If / flow cytometry, IHC, IP / ChIP ELISA, and more)
GenScript has 12-year track record of custom monoclonal antibody production services, generating thousands of successful custom monoclonal antibodies with high-specificity and high-affinity. With our new MonoExpress™ Premium monoclonal antibody production services, you get to test 10 hybridoma supernatants and choose up to 5 clones that actually work for your own applications. No matter your application is Western Blot, IF/flow cytometry, IHC, ICC, IP/ChIP, Sandwich ELISA, or functional assays, we guarantee that at least one clone will work in your own experimental system. Read more »
MonoExpress™ Premium package uses protein as antigen, the gold standard when it comes to high-quality monoclonal antibody production. Protein antigens result in monoclonal antibodies against multiple conformational epitopes of the target protein, maximizing the chances your antibody will work for a variety of applications. To get started, simply provide your target protein sequence; we start with protein antigen production all the way to the production of application guaranteed monoclonal antibodies. MonoExpress™ Gold, Silver, and Bronze monoclonal antibody production services use peptides as antigens and all MonoExpress™ packages come with superior ELISA guarantees. Plus, you'll receive your antibody or hybridoma cell line 4 months faster than traditional immunization protocols.
Monoclonal antibody production using protein as antigen
Protein antigens are the elite choice when it comes to high-quality monoclonal antibody production. Their unique ability to elicit monoclonal antibodies that recognize the native confirmation of the target protein makes them a superior choice over other antigen strategies. Our popular application-guaranteed MonoExpress™ Premium monoclonal antibody production package exemplifies the high success rate of protein antigens by offering the unprecedented guarantee that at least one clone will work in your own experimental system.
+ Additional clones may be purchased at $399/clone.
Monoclonal antibody production using peptide as antigen
In cases where access to a target protein is limited or unavailable, but the amino acid sequence is known, peptide antigens offer a smart solution for monoclonal antibody production. Peptide antigens are also ideal for producing monoclonal antibodies against post-translational modification sites within a target protein.
++ Purified mAb may be purchased at $399 for 2 mg purified mAb/clone.
The antibody generated by conventional immunization protocol had weak specificity to acetylated peptide antigens and cross-reactivity with corresponding non-acetylated peptide antigens.
MonoExpress™ antibodies had high specificity to acetylated peptide antigens and no cross-reactivity with corresponding non-acetylated peptide antigens.
The antibodies generated by conventional immunization protocol each having a weak binding specificity is shown:
A panel of monoclonal antibodies each having a unique binding specificity is shown:
Affinity analysis of a monoclonal antibody generated by MonoExpress™ Antibody Services.
Biacore antibody/antigen affinity analysis showed that the MonoExpress™ generated antibody exhibited an equal or greater affinity to its complementary antigen, compared to an antibody generated by conventional immunization. Typically monoclonal antibodies generated by MonoExpress™ services display reasonably high affinities to their target antigens.
*Read about our safety net policy
If a successful clone cannot be found, customer has the following options:
For problematic antigens check out our DNA Immunization Service.
If none of these standard packages fit your requirements, we offer fully Customized Monoclonal Antibody Services
For a general overview of our variety of monoclonal antibody services, click here.
Unsure which service line is appropriate for your application? Try our Antibody Service Selection Tool.
Our customer service representatives are available 24 hours a day, Monday through Friday to assist you.
Please contact us if you need immediate assistance.
Please contact us (phone: 1-877-436-7274 or email: firstname.lastname@example.org),if you need immediate assistance.