Overview

Leveraging the cell line development capabilities, GenScript has developed single-clone derived CHO-K1 cell lines expressing different classes of Fc gamma receptors (FcγRs) and neonatal Fc receptor (FcRn). The Fc receptor cell line portfolio now includes ten cell lines that express one human FcRn, and six human FcγRs containing polymorphic variants of FcγRIIIa, FcγRIIa and FcγRIIb.

Highlights

Most Complete Offering

Most Complete Offering

Single Clone

Single Clone

Guaranteed Performance

Guaranteed Performance

Polymorphic Variants

Polymorphic Variants

Applications

Determination of binding affinity of antibodies or Fc fusion proteins.

Determination of half-life of antibodies or Fc fusion proteins.

Determination of mechanism of action of antibodies or Fc fusion proteins in vitro.

Product List

Gene Receptor Alias Cell Line Cat.No.
FCGR3A FcγRIIIa CD16A CHO-K1/CD16A 158F
CHO-K1/CD16A 158V
FCGR3B FcγRIIIb CD16B CHO-K1/CD16B
FCGR2A FcγRIIa CD32A CHO-K1/CD32A 131H
CHO-K1/CD32A 131R
FCGR2B FcγRIIb CD32B CHO-K1/CD32B 232I
CHO-K1/CD32B 232T
FCGR2C FcγRIIc CD32C CHO-K1/CD32C 13Gln
FCGR1 FcγRI CD64 CHO-K1/CD64
FCGRT FcRn - CHO-K1/FcRn

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