Home » CRISPR Services » CRISPR sgRNA Database

Interactive CRISPR gRNA design tool

sgRNA designed on-demand for any DNA sequence you input

algorithm developed and validated by Feng Zhang lab,Broad Institute

Genome-wide gRNA databases for CRISPR genome editing and transcription activation

To facilitate your research using CRISPR technology, GenScript provides genome-wide databases containing pre-validated gRNA sequences design by the Broad Institute of Harvard and MIT. If you want to view all, please click gRNA list.

Genome Editing Applications

Search database for SpCas9 gRNA sequences

Species:	Our online genome-wide gRNA databases offer validated sgRNA sequences for genome editing with WT SpCas9 in Human or Mouse, or for SAM transcription activation in Human only. Our scientists offer complimentary expert design of gRNA for any coding or non-coding region in any species; please email your request to gene@genscript.com.
Gene:	Note: Please do not use GI number or NM/XM number here. Please enter the Gene name, Gene symbol or Gene ID as found in http://www.ncbi.nlm.nih.gov/gene.

Transcription Activation

Search database for SAM gRNA sequences

Species:	Our online genome-wide gRNA databases offer validated sgRNA sequences for genome editing with WT SpCas9 in Human or Mouse, or for SAM transcription activation in Human only. Our scientists offer complimentary expert design of gRNA for any coding or non-coding region in any species; please email your request to gene@genscript.com.
Gene:	Note: Please do not use GI number or NM/XM number here. Please enter the Gene name, Gene symbol or Gene ID as found in http://www.ncbi.nlm.nih.gov/gene.

Ready for delivery: More than 20,000 gRNA constructs are in-stock and ready for delivery at $99/clone.
Full-Genome Coverage:
- GenScript's gRNA Database contains 6 unique, pre-validated gRNA sequences targeting each of the 19,050 genes in the human genome and 20,611 genes in the mouse genome. SpCas9 gRNA sequences are targeted to constitutive exons and designed for minimal off-target effects.
- GenScript's SAM Database contains 6 unique, pre-validated gRNA sequences targeting each of the 19,050 genes in the human genome. SAM gRNA sequences target the first 200bp upstream of each transcription start site.

CRISPR Products and Services at GenScript

New! CRISPR crRNA/Cas9 Protein Reagents

Customizable, DNA-free, ready-for-transfection crRNA/Cas9 particles.

CRISPR Plasmids DNA plasmids for single guide RNA and/or Cas9 expression		Cell Line Gene Editing Validated knock-out cell line service using CRISPR technology.
CRISPR Libraries Genome-wide or pathway-specific CRISPR knock-out or activation libraries for screening experiments.		Microbial Gene Editing Validated knock-out and knock-in mutagenesis in bacteria and yeast.