DNA Microarrays Enable New CRISPR/Cas9-based Peptide Library Display
Sep 13, 2021

News

DNA Microarrays Enable New CRISPR/Cas9-based Peptide Library Display

Learn about a new CRISPR/Cas9 application leveraging its RNA guided specificity to self-assemble peptide fused and inactivated Cas9 onto DNA microarrays.

Gene Therapy for AADC: Targeting Neurons with AAV Vectors
Aug 31, 2021

News

Gene Therapy for AADC: Targeting Neurons with AAV Vectors

Learn how AAV2-hAADC gene therapy targeting dopamine neurons in the midbrain allowed restoring motor function in AADC patients.

Lentiviral-Modified Cells for Rare Disease Therapy: Autologous HPSC therapy for SCID-ADA
Aug 16, 2021

Resource

Lentiviral-Modified Cells for Rare Disease Therapy: Autologous HPSC therapy for SCID-ADA

Learn how lentiviral vectors promise to offer a safer gene delivery approach for correction of immunological deficits in SCID-ADA.

Quadrivalent Hemagglutinin Nanoparticles
Aug 02, 2021

News

Quadrivalent Hemagglutinin Nanoparticles

Learn how an influenza hemagglutinin nanoparticle vaccine protects against influenza viral strains by inducing broad neutralizing antibodies.

Evolving CRISPR/Cas Tools through Engineering Strategies
Jul 19, 2021

News

Evolving CRISPR/Cas Tools through Engineering Strategies

Learn how structure-guided modifications to CRISPR/Cas12a and Cas9 in the Kleinstiver lab have expanded access to genome sequences by expanding PAM preferences.

Correcting Human Disease Mutations with CRISPR/Cas9-AAV Strategies
Jul 15, 2021

News

Correcting Human Disease Mutations with CRISPR/Cas9-AAV Strategies

The Porteus lab is developing gene editing strategies to correct disease causing mutations. His lab focuses on modifying stem cells through the combined use of CRISPR/Cas9 gene editing tools and AAV vectors for payload delivery. Following ex vivo

Viral and Non-Viral Gene Therapies for Inherited Retinal Disease
Jul 06, 2021

News

Viral and Non-Viral Gene Therapies for Inherited Retinal Disease

Inherited retinal diseases are due to mutations in a broad range of genes leading to partial or total vision loss. Learn how genes are delivered for therapy.

Maximizing Biofuel Production in the Yeast R. toruloides through Metabolic Engineering
Jun 08, 2021

News

Maximizing Biofuel Production in the Yeast R. toruloides through Metabolic Engineering

Learn how high throughput DNA assembly helps expedite metabolic engineering for biofuel pathway optimization in microbes.

Genetically Engineered Immune Cells
Jun 08, 2021

News

Genetically Engineered Immune Cells

Genetically engineered immune cells have gained attention as they have become an increasingly effective approach against some cancer types

Novavax Vaccine Candidate Advancing through Clinical Studies
Apr 14, 2021

Resource

Novavax Vaccine Candidate Advancing through Clinical Studies

Based on the COVID-19 dashboard by the Center for Systems Science and Engineering (CSSE) at Johns Hopkins University, there are over 124 million cases of COVD-19 globally, and over 2.7 million people have died from the disease.

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