Molecular Biology News

Learn about a new CRISPR/Cas9 application leveraging its RNA guided specificity to self-assemble peptide fused and inactivated Cas9 onto DNA microarrays.

Learn how AAV2-hAADC gene therapy targeting dopamine neurons in the midbrain allowed restoring motor function in AADC patients.

Learn how lentiviral vectors promise to offer a safer gene delivery approach for correction of immunological deficits in SCID-ADA.

Learn how an influenza hemagglutinin nanoparticle vaccine protects against influenza viral strains by inducing broad neutralizing antibodies.

Learn how structure-guided modifications to CRISPR/Cas12a and Cas9 in the Kleinstiver lab have expanded access to genome sequences by expanding PAM preferences.

The Porteus lab is developing gene editing strategies to correct disease causing mutations. His lab focuses on modifying stem cells through the combined use of CRISPR/Cas9 gene editing tools and AAV vectors for payload delivery. Following ex vivo

Inherited retinal diseases are due to mutations in a broad range of genes leading to partial or total vision loss. Learn how genes are delivered for therapy.

Learn how high throughput DNA assembly helps expedite metabolic engineering for biofuel pathway optimization in microbes.

Genetically engineered immune cells have gained attention as they have become an increasingly effective approach against some cancer types

Based on the COVID-19 dashboard by the Center for Systems Science and Engineering (CSSE) at Johns Hopkins University, there are over 124 million cases of COVD-19 globally, and over 2.7 million people have died from the disease.