MYOC cDNA ORF clone, Bos taurus(cattle)
Gene Symbol | MYOC |
Entrez Gene ID | 281342 |
Full Name | myocilin |
General protein information |
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Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
mRNA and Protein(s)
mRNA | Protein | Name |
---|---|---|
NM_174118.2 | NP_776543.2 | myocilin precursor |

Homo sapiens (human) | MYOC | NP_000252.1 |
MYOC | XP_001099905.1 | |
Danio rerio (zebrafish) | myoc | NP_001015062.1 |
Mus musculus (house mouse) | Myoc | NP_034995.3 |
Gallus gallus (chicken) | MYOC | XP_422235.4 |
Xenopus tropicalis (tropical clawed frog) | myoc | XP_002934195.2 |
Pan troglodytes (chimpanzee) | MYOC | XP_513995.2 |
Canis lupus familiaris (dog) | MYOC | NP_001041495.2 |
Bos taurus (cattle) | MYOC | NP_776543.2 |
Rattus norvegicus (Norway rat) | Myoc | NP_110492.1 |

Related articles in PubMed
A whole-genome assembly of the domestic cow, Bos taurus.
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Mar?ais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL
Genome biology10(4)R42(2009)
Myocilin mutations causing glaucoma inhibit the intracellular endoproteolytic cleavage of myocilin between amino acids Arg226 and Ile227.
Aroca-Aguilar JD, S?nchez-S?nchez F, Ghosh S, Coca-Prados M, Escribano J
The Journal of biological chemistry280(22)21043-51(2005 Jun)
Molecular cloning of the bovine MYOC and induction of its expression in trabecular meshwork cells.
Taniguchi F, Suzuki Y, Kurihara H, Kurihara Y, Kasai H, Shirato S, Araie M
Investigative ophthalmology & visual science41(8)2070-5(2000 Jul)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
endoproteolytic processing might regulate the activity of myocilin; the inhibition of the processing by pathogenic mutations impairs the normal role of myocilin
Title: Myocilin mutations causing glaucoma inhibit the intracellular endoproteolytic cleavage of myocilin between amino acids Arg226 and Ile227.
The following MYOC gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the MYOC cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OBa01436 | |
Clone ID Related Accession (Same CDS sequence) | NM_174118.2 | |
Accession Version | NM_174118.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1473bp) Protein sequence SNP |
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Vector | pcDNA3.1+/C-(K)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-24 | |
Organism | Bos taurus(cattle) | |
Product | myocilin precursor | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC104571.1. On Sep 18, 2005 this sequence version replaced NM_174118.1. ##Evidence-Data-START## Transcript exon combination :: BC104571.1, AB027758.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03145441 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGCCAGCGG TCCAGCTGCT ACTGCTGGCC TGTCTGCTAG GGGGTGTGGG GGCCAGGACA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_776543.2 |
CDS | 96..1568 |
Translation |

Target ORF information:
Target ORF information:
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ORF Insert Sequence:
1 | ATGCCAGCGG TCCAGCTGCT ACTGCTGGCC TGTCTGCTAG GGGGTGTGGG GGCCAGGACA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
![]() |
A whole-genome assembly of the domestic cow, Bos taurus. |
![]() |
Myocilin mutations causing glaucoma inhibit the intracellular endoproteolytic cleavage of myocilin between amino acids Arg226 and Ile227. |
![]() |
Molecular cloning of the bovine MYOC and induction of its expression in trabecular meshwork cells. |