Gene Symbol | IGFBP5 |
Entrez Gene ID | 404185 |
Full Name | insulin like growth factor binding protein 5 |
General protein information |
|
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
ORF » Species Summary » Bos taurus » IGFBP5 cDNA ORF clone
gRNAs
Gene Symbol | IGFBP5 |
Entrez Gene ID | 404185 |
Full Name | insulin like growth factor binding protein 5 |
General protein information |
|
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
mRNA | Protein | Name |
---|---|---|
XM_010802317.2 | XP_010800619.1 | insulin-like growth factor-binding protein 5 isoform X1 |
NM_001105327.2 | NP_001098797.1 | insulin-like growth factor-binding protein 5 precursor |
XM_010802317.1 | XP_010800619.1 | insulin-like growth factor-binding protein 5 isoform X1 |
Bos taurus (cattle) | IGFBP5 | NP_001098797.1 |
Mus musculus (house mouse) | Igfbp5 | NP_034648.2 |
Xenopus tropicalis (tropical clawed frog) | igfbp5 | NP_001016042.1 |
Canis lupus familiaris (dog) | IGFBP5 | XP_852885.1 |
Gallus gallus (chicken) | IGFBP5 | XP_422069.3 |
IGFBP5 | XP_001087664.1 | |
Danio rerio (zebrafish) | igfbp5b | NP_001092224.1 |
Homo sapiens (human) | IGFBP5 | NP_000590.1 |
Pan troglodytes (chimpanzee) | IGFBP5 | XP_003309513.1 |
Rattus norvegicus (Norway rat) | Igfbp5 | NP_036949.1 |
Danio rerio (zebrafish) | igfbp5a | NP_001119935.1 |
miR-143 regulates proliferation and differentiation of bovine skeletal muscle satellite cells by targeting IGFBP5.
Zhang WR, Zhang HN, Wang YM, Dai Y, Liu XF, Li X, Ding XB, Guo H
In vitro cellular & developmental biology. Animal53(3)265-271(2017 Mar)
Comparative expression profiling of insulin-like growth factor binding protein-5 in milk of Bos indicus and Bubalus bubalis during lactation.
Mohapatra SK, Singh S, Kumar S, Dang AK, Datta TK, Das SK, Mohanty TK, Kaushik JK, Mohanty AK
Animal : an international journal of animal bioscience9(4)643-9(2015 Apr)
A whole-genome assembly of the domestic cow, Bos taurus.
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Mar?ais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL
Genome biology10(4)R42(2009)
Growth hormone suppresses the expression of IGFBP-5, and promotes the IGF-I-induced phosphorylation of Akt in bovine mammary epithelial cells.
Sakamoto K, Yano T, Kobayashi T, Hagino A, Aso H, Obara Y
Domestic animal endocrinology32(4)260-72(2007 May)
Alterations in follicular IGFBP mRNA expression and follicular fluid IGFBP concentrations during the first follicle wave in beef heifers.
Canty MJ, Boland MP, Evans AC, Crowe MA
Animal reproduction science93(3-4)199-217(2006 Jul)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
IGFBP5, an important component of IGF signaling pathway, contributes greatly to bovine muscle cell development. A mechanism that miR-143 can regulate the proliferation and differentiation of bovine MSCs through changing expression of IGFBP5 was elucidated by our study.
Title: miR-143 regulates proliferation and differentiation of bovine skeletal muscle satellite cells by targeting IGFBP5.
This study suggested that that higher level IGFBP-5 expression may have functional significance in lactation persistency.
Title: Comparative expression profiling of insulin-like growth factor binding protein-5 in milk of Bos indicus and Bubalus bubalis during lactation.
GH reduces mRNA and protein expression of IGFBP-5 in bovine mammary epithelial cells, but it does not affect the expression of IGFBP-3
Title: Growth hormone suppresses the expression of IGFBP-5, and promotes the IGF-I-induced phosphorylation of Akt in bovine mammary epithelial cells.
follicular dominance was associated with low or decreased follicular fluid concentrations of IGFBP-4 and -5
Title: Alterations in follicular IGFBP mRNA expression and follicular fluid IGFBP concentrations during the first follicle wave in beef heifers.
The following IGFBP5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the IGFBP5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OBa00738 | |
Clone ID Related Accession (Same CDS sequence) | NM_001105327.2 | |
Accession Version | NM_001105327.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 816bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-25 | |
Organism | Bos taurus(cattle) | |
Product | insulin-like growth factor-binding protein 5 precursor | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC149394.1. On Aug 31, 2012 this sequence version replaced NM_001105327.1. ##Evidence-Data-START## Transcript exon combination :: BC149394.1, DN511652.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03145425, SAMN03145448 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGTGCTCA CCGCGGTCCT CCTTCTTCTG GCCGCCTGTG CGGGATCGGC CCAGGGTCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001098797.1 |
CDS | 31..846 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGTGCTCA CCGCGGTCCT CCTTCTTCTG GCCGCCTGTG CGGGATCGGC CCAGGGTCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa45655 | |
Clone ID Related Accession (Same CDS sequence) | XM_010802317.2 , XM_010802317.1 | |
Accession Version | XM_010802317.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 867bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2018-05-06 | |
Organism | Bos taurus(cattle) | |
Product | insulin-like growth factor-binding protein 5 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037329.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On May 7, 2018 this sequence version replaced XM_010802317.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGTGCTCA CCGCGGTCCT CCTTCTTCTG GCCGCCTGTG CGGGATCGGC CCAGGGTCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_010800619.1 |
CDS | 977..1843 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGTGCTCA CCGCGGTCCT CCTTCTTCTG GCCGCCTGTG CGGGATCGGC CCAGGGTCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa45655 | |
Clone ID Related Accession (Same CDS sequence) | XM_010802317.2 , XM_010802317.1 | |
Accession Version | XM_010802317.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 867bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | ![]() |
Clone information | Clone Map | ![]() |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-01-25 | |
Organism | Bos taurus(cattle) | |
Product | insulin-like growth factor-binding protein 5 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003103849.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Bos taurus Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGTGCTCA CCGCGGTCCT CCTTCTTCTG GCCGCCTGTG CGGGATCGGC CCAGGGTCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_010800619.1 |
CDS | 217..1083 |
Translation |
Target ORF information:
Target ORF information:
|
![]() |
1 | ATGGTGCTCA CCGCGGTCCT CCTTCTTCTG GCCGCCTGTG CGGGATCGGC CCAGGGTCTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
miR-143 regulates proliferation and differentiation of bovine skeletal muscle satellite cells by targeting IGFBP5. |
Comparative expression profiling of insulin-like growth factor binding protein-5 in milk of Bos indicus and Bubalus bubalis during lactation. |
A whole-genome assembly of the domestic cow, Bos taurus. |
Growth hormone suppresses the expression of IGFBP-5, and promotes the IGF-I-induced phosphorylation of Akt in bovine mammary epithelial cells. |
Alterations in follicular IGFBP mRNA expression and follicular fluid IGFBP concentrations during the first follicle wave in beef heifers. |