| Gene Symbol | appl1 |
| Entrez Gene ID | 571540 |
| Full Name | adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 1 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Danio rerio(zebrafish) |
The following appl1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the appl1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | ODa04720 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001128074.1 | |
| Accession Version | NM_001128074.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2124bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2017-06-24 | |
| Organism | Danio rerio(zebrafish) | |
| Product | DCC-interacting protein 13-alpha | |
| Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from EU053152.1. On Jul 31, 2008 this sequence version replaced XR_029597.2. ##Evidence-Data-START## Transcript exon combination :: EU053152.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2168446, SAMEA2168447 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGCCTGGAA TCGATAAACT ACCGATAGAG GAAACTCTGG AGGACAGTCC GCAGACTCGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001121546.1 |
| CDS | 43..2166 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_001128074.1 |
1 | ATGCCTGGAA TCGATAAACT ACCGATAGAG GAAACTCTGG AGGACAGTCC GCAGACTCGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | ODa147909 | |
| Clone ID Related Accession (Same CDS sequence) | XM_021479657.1 | |
| Accession Version | XM_021479657.1 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2127bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2017-06-14 | |
| Organism | Danio rerio(zebrafish) | |
| Product | DCC-interacting protein 13-alpha isoform X1 | |
| Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_007122.7) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Danio rerio Annotation Release 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## | |
1 | ATGCCTGGAA TCGATAAACT ACCGATAGAG GAAACTCTGG AGGACAGTCC GCAGACTCGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | XP_021335332.1 |
| CDS | 98..2224 |
| Translation |
Target ORF information:
Target ORF information:
|
XM_021479657.1 |
1 | ATGCCTGGAA TCGATAAACT ACCGATAGAG GAAACTCTGG AGGACAGTCC GCAGACTCGT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Reverse genetic screening reveals poor correlation between morpholino-induced and mutant phenotypes in zebrafish. |
Altering PI3K-Akt signalling in zebrafish embryos affects PTEN phosphorylation and gastrulation. |
The endosomal protein Appl1 mediates Akt substrate specificity and cell survival in vertebrate development. |
