Gene Symbol | SPON1 |
Entrez Gene ID | 10418 |
Full Name | spondin 1 |
Synonyms | VSGP/F-spondin,f-spondin |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
ORF » Species Summary » Homo sapiens » SPON1 cDNA ORF clone
Gene Symbol | SPON1 |
Entrez Gene ID | 10418 |
Full Name | spondin 1 |
Synonyms | VSGP/F-spondin,f-spondin |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome | |
Disorder MIM: |
mRNA | Protein | Name |
---|---|---|
NM_006108.3 | NP_006099.2 | spondin-1 precursor |
NM_006108.4 | NP_006099.2 | spondin-1 precursor |
SPON1 | XP_001093336.1 | |
Mus musculus (house mouse) | Spon1 | NP_663559.1 |
Xenopus tropicalis (tropical clawed frog) | spon1 | NP_001090741.1 |
Homo sapiens (human) | SPON1 | NP_006099.2 |
Rattus norvegicus (Norway rat) | Spon1 | NP_742064.1 |
Gallus gallus (chicken) | SPON1 | NP_990182.1 |
Danio rerio (zebrafish) | spon1a | NP_571590.1 |
Drosophila melanogaster (fruit fly) | CG17739 | NP_610757.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP012307 | XP_320234.3 |
Pan troglodytes (chimpanzee) | SPON1 | XP_508295.3 |
Canis lupus familiaris (dog) | SPON1 | XP_534067.2 |
Bos taurus (cattle) | SPON1 | NP_777168.1 |
Genome-Wide Pharmacogenomic Study on Methadone Maintenance Treatment Identifies SNP rs17180299 and Multiple Haplotypes on CYP2B6, SPON1, and GSG1L Associated with Plasma Concentrations of Methadone R- and S-enantiomers in Heroin-Dependent Patients.
Yang HC, Chu SK, Huang CL, Kuo HW, Wang SC, Liu SW, Ho IK, Liu YL
PLoS genetics12(3)e1005910(2016 Mar)
Spondin 1 promotes metastatic progression through Fak and Src dependent pathway in human osteosarcoma.
Chang H, Dong T, Ma X, Zhang T, Chen Z, Yang Z, Zhang Y
Biochemical and biophysical research communications464(1)45-50(2015 Aug)
Genome-wide association study of ancestry-specific TB risk in the South African Coloured population.
Chimusa ER, Zaitlen N, Daya M, M?ller M, van Helden PD, Mulder NJ, Price AL, Hoal EG
Human molecular genetics23(3)796-809(2014 Feb)
Experimental validation of 5 in-silico predicted glioma biomarkers.
Towner RA, Jensen RL, Vaillant B, Colman H, Saunders D, Giles CB, Wren JD
Neuro-oncology15(12)1625-34(2013 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
gene expression experiment revealed that CYP2B6, SPON1, and GSG1L can be activated concomitantly through a constitutive androstane receptor (CAR) activation pathway
Title: Genome-Wide Pharmacogenomic Study on Methadone Maintenance Treatment Identifies SNP rs17180299 and Multiple Haplotypes on CYP2B6, SPON1, and GSG1L Associated with Plasma Concentrations of Methadone R- and S-enantiomers in Heroin-Dependent Patients.
SPON1 promotes metastatic progression through Fak and Src dependent pathway in human osteosarcoma.
Title: Spondin 1 promotes metastatic progression through Fak and Src dependent pathway in human osteosarcoma.
These data suggest that SPON1 may be associated with the differential rate of cognitive decline in Alzheimer disease.
Title: Genome-wide association study of the rate of cognitive decline in Alzheimer's disease.
High SPON1 expression is associated with high-grade gliomas.
Title: Experimental validation of 5 in-silico predicted glioma biomarkers.
Genome-wide scan of healthy human connectome discovers SPON1 gene variant influencing dementia severity
Title: Genome-wide scan of healthy human connectome discovers SPON1 gene variant influencing dementia severity.
The following SPON1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SPON1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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CloneID | OHu15605 | |
Clone ID Related Accession (Same CDS sequence) | NM_006108.3 , NM_006108.4 | |
Accession Version | NM_006108.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2424bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-08-05 | |
Organism | Homo sapiens(human) | |
Product | spondin-1 precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AK291780.1, AB018305.2 and BQ026865.1. On Nov 22, 2018 this sequence version replaced NM_006108.3. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803615.147701.1, SRR1803611.213743.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000576479.4/ ENSP00000460236.1 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length. |
1 | ATGAGGCTGT CCCCGGCGCC CCTGAAGCTG AGCCGGACTC CGGCACTGCT GGCCCTGGCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_006099.2 |
CDS | 183..2606 |
Translation |
Target ORF information:
Target ORF information:
|
NM_006108.4 |
1 | ATGAGGCTGT CCCCGGCGCC CCTGAAGCTG AGCCGGACTC CGGCACTGCT GGCCCTGGCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu15605 | |
Clone ID Related Accession (Same CDS sequence) | NM_006108.3 , NM_006108.4 | |
Accession Version | NM_006108.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2424bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-10-02 | |
Organism | Homo sapiens(human) | |
Product | spondin-1 precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA965056.1, AK291780.1, AB018305.2 and BQ026865.1. On Aug 23, 2011 this sequence version replaced NM_006108.2. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: SRR1803611.213743.1, SRR1803616.250876.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1966682, SAMEA1968189 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end. |
1 | ATGAGGCTGT CCCCGGCGCC CCTGAAGCTG AGCCGGACTC CGGCACTGCT GGCCCTGGCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_006099.2 |
CDS | 269..2692 |
Translation |
Target ORF information:
Target ORF information:
|
NM_006108.3 |
1 | ATGAGGCTGT CCCCGGCGCC CCTGAAGCTG AGCCGGACTC CGGCACTGCT GGCCCTGGCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome-Wide Pharmacogenomic Study on Methadone Maintenance Treatment Identifies SNP rs17180299 and Multiple Haplotypes on CYP2B6, SPON1, and GSG1L Associated with Plasma Concentrations of Methadone R- and S-enantiomers in Heroin-Dependent Patients. |
Spondin 1 promotes metastatic progression through Fak and Src dependent pathway in human osteosarcoma. |
Genome-wide association study of ancestry-specific TB risk in the South African Coloured population. |
Experimental validation of 5 in-silico predicted glioma biomarkers. |