| Gene Symbol | DCUN1D3 |
| Entrez Gene ID | 123879 |
| Full Name | defective in cullin neddylation 1 domain containing 3 |
| Synonyms | 44M2.4,SCCRO3 |
| General protein information |
|
| Gene Type | protein-coding |
| Organism | Homo sapiens(human) |
| Genome | |
| Disorder MIM: |
The following DCUN1D3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the DCUN1D3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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| CloneID | OHu07251 |
|
| Clone ID Related Accession (Same CDS sequence) | NM_173475.3 , NM_173475.2 , NM_173475.4 | |
| Accession Version | NM_173475.3 | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 915bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector |  User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2017-10-02 | |
| Organism | Homo sapiens(human) | |
| Product | DCN1-like protein 3 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA545688.1, BC040442.1, AC002394.1, AC004381.1 and AK027199.1. On Apr 12, 2016 this sequence version replaced NM_173475.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1660809.13472.1, SRR1803611.205494.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1965299, SAMEA1966682 [ECO:0000348] ##Evidence-Data-END## | |
1 | ATGGGCCAGT GTGTCACCAA GTGTAAGAAT CCCTCATCGA CCCTGGGCAG CAAAAATGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_775746.1 |
| CDS | 261..1175 |
| Translation |
Target ORF information:
Target ORF information:
|
 NM_173475.3 |
1 | ATGGGCCAGT GTGTCACCAA GTGTAAGAAT CCCTCATCGA CCCTGGGCAG CAAAAATGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OHu07251 |
|
| Clone ID Related Accession (Same CDS sequence) | NM_173475.3 , NM_173475.2 , NM_173475.4 | |
| Accession Version | NM_173475.2 | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 915bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2015-05-04 | |
| Organism | Homo sapiens(Human) | |
| Product | DCN1-like protein 3 | |
| Comment | ||
1 | ATGGGCCAGT GTGTCACCAA GTGTAAGAAT CCCTCATCGA CCCTGGGCAG CAAAAATGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_775746.1 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_173475.2 |
1 | ATGGGCCAGT GTGTCACCAA GTGTAAGAAT CCCTCATCGA CCCTGGGCAG CAAAAATGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OHu07251 |
|
| Clone ID Related Accession (Same CDS sequence) | NM_173475.3 , NM_173475.2 , NM_173475.4 | |
| Accession Version | NM_173475.4 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 915bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-08-05 | |
| Organism | Homo sapiens(human) | |
| Product | DCN1-like protein 3 | |
| Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA545688.1, BC040442.1, AC002394.1, AC004381.1 and AK027199.1. On Nov 23, 2018 this sequence version replaced NM_173475.3. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1660809.13472.1, BC040442.1 [ECO:0000332] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000324344.9/ ENSP00000319482.3 RefSeq Select criteria :: based on single protein-coding transcript ##RefSeq-Attributes-END## COMPLETENESS: full length. | |
1 | ATGGGCCAGT GTGTCACCAA GTGTAAGAAT CCCTCATCGA CCCTGGGCAG CAAAAATGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_775746.1 |
| CDS | 261..1175 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_173475.4 |
1 | ATGGGCCAGT GTGTCACCAA GTGTAAGAAT CCCTCATCGA CCCTGGGCAG CAAAAATGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
DCUN1D3 activates SCFSKP2 ubiquitin E3 ligase activity and cell cycle progression under UV damage. |
SCCRO3 (DCUN1D3) antagonizes the neddylation and oncogenic activity of SCCRO (DCUN1D1). |
The human Dcn1-like protein DCNL3 promotes Cul3 neddylation at membranes. |
DCUN1D3, a novel UVC-responsive gene that is involved in cell cycle progression and cell growth. |
The conserved protein DCN-1/Dcn1p is required for cullin neddylation in C. elegans and S. cerevisiae. |
