Gene Symbol | SYNPR |
Entrez Gene ID | 132204 |
Full Name | synaptoporin |
Synonyms | SPO |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome |
ORF » Species Summary » Homo sapiens » SYNPR cDNA ORF clone
Gene Symbol | SYNPR |
Entrez Gene ID | 132204 |
Full Name | synaptoporin |
Synonyms | SPO |
General protein information |
|
Gene Type | protein-coding |
Organism | Homo sapiens(human) |
Genome |
mRNA | Protein | Name |
---|---|---|
NM_144642.4 | NP_653243.1 | synaptoporin isoform 2 precursor |
XM_017005731.1 | XP_016861220.1 | synaptoporin isoform X1 |
NM_001130003.2 | NP_001123475.1 | synaptoporin isoform 1 |
XM_017005732.2 | XP_016861221.1 | synaptoporin isoform X2 |
XM_017005732.1 | XP_016861221.1 | synaptoporin isoform X2 |
NM_001130003.1 | NP_001123475.1 | synaptoporin isoform 1 |
NM_144642.5 | NP_653243.1 | synaptoporin isoform 2 precursor |
Canis lupus familiaris (dog) | SYNPR | XP_003432857.1 |
Mus musculus (house mouse) | Synpr | NP_082328.3 |
Homo sapiens (human) | SYNPR | NP_001123475.1 |
SYNPR | XP_001093248.2 | |
Gallus gallus (chicken) | SYNPR | NP_990725.1 |
Pan troglodytes (chimpanzee) | SYNPR | XP_001174562.1 |
Rattus norvegicus (Norway rat) | Synpr | NP_076464.1 |
Danio rerio (zebrafish) | LOC558290 | XP_686583.4 |
Bos taurus (cattle) | SYNPR | NP_001039971.1 |
Xenopus tropicalis (tropical clawed frog) | synpr | NP_001072689.1 |
Genome-wide association study of maternal and inherited effects on left-sided cardiac malformations.
Mitchell LE, Agopian AJ, Bhalla A, Glessner JT, Kim CE, Swartz MD, Hakonarson H, Goldmuntz E
Human molecular genetics24(1)265-73(2015 Jan)
Cloning and sequence analysis of the human cDNA encoding the synaptoporin (delta), a highly conservative synaptic vesicle protein.
Dai J, Ji C, Gu S, Wu Q, Wang L, Xu J, Zeng L, Ye X, Yin G, Xie Y, Mao Y
Molecular biology reports30(3)185-91(2003 Sep)
Tyrosine nitration of a synaptic protein synaptophysin contributes to amyloid beta-peptide-induced cholinergic dysfunction.
Tran MH, Yamada K, Nakajima A, Mizuno M, He J, Kamei H, Nabeshima T
Molecular psychiatry8(4)407-12(2003 Apr)
Synaptic vesicle protein synaptoporin is differently expressed by subpopulations of mouse hippocampal neurons.
Singec I, Knoth R, Ditter M, Hagemeyer CE, Rosenbrock H, Frotscher M, Volk B
The Journal of comparative neurology452(2)139-53(2002 Oct)
Expression of the synaptophysin gene family is not restricted to neuronal and neuroendocrine differentiation in rat and human.
Leube RE
Differentiation; research in biological diversity56(3)163-71(1994 May)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Results from genome-wide association studies identify synaptoporin gene as one of the three susceptibility loci candidate for congenital left-sided lesions.
Title: Genome-wide association study of maternal and inherited effects on left-sided cardiac malformations.
Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)
Title: Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score.
cloning and characterization of the human cDNA that encodes the human homologue of synaptoporin
Title: Cloning and sequence analysis of the human cDNA encoding the synaptoporin (delta), a highly conservative synaptic vesicle protein.
Tyrosine nitration of synaptophysin is related to Amyloid beta induced impairment of acetylcholine release.
Title: Tyrosine nitration of a synaptic protein synaptophysin contributes to amyloid beta-peptide-induced cholinergic dysfunction.
The following SYNPR gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SYNPR cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
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CloneID | OHu31464 | |
Clone ID Related Accession (Same CDS sequence) | NM_144642.4 , NM_144642.5 | |
Accession Version | NM_144642.4 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 798bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-02-17 | |
Organism | Homo sapiens(human) | |
Product | synaptoporin isoform 2 precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA505318.1, AL834457.1 and AF411860.2. On Jul 10, 2008 this sequence version replaced NM_144642.3. Transcript Variant: This variant (2) uses an alternate exon in the 5' CDS, compared to variant 1. It encodes isoform 2, which is shorter and has a distinct N-terminus, compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: BC022518.1, SRR1803614.63338.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145743, SAMEA2154665 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGTGTATGG TGATATTTGC TCCGCTTTTT GCAATCTTTG CATTTGCAAC ATGCGGTGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_653243.1 |
CDS | 370..1167 |
Translation |
Target ORF information:
Target ORF information:
|
NM_144642.4 |
1 | ATGTGTATGG TGATATTTGC TCCGCTTTTT GCAATCTTTG CATTTGCAAC ATGCGGTGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu31464 | |
Clone ID Related Accession (Same CDS sequence) | NM_144642.4 , NM_144642.5 | |
Accession Version | NM_144642.5 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 798bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-09-27 | |
Organism | Homo sapiens(human) | |
Product | synaptoporin isoform 2 precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DA505318.1, AL834457.1, AF411860.2 and AC104436.2. On May 31, 2019 this sequence version replaced NM_144642.4. Transcript Variant: This variant (2) uses an alternate exon in the 5' CDS, compared to variant 1. It encodes isoform 2, which is shorter and has a distinct N-terminus, compared to isoform 1. ##Evidence-Data-START## Transcript exon combination :: SRR1660805.33694.1, SRR1803612.8333.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA2145743, SAMEA2154665 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGTGTATGG TGATATTTGC TCCGCTTTTT GCAATCTTTG CATTTGCAAC ATGCGGTGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_653243.1 |
CDS | 135..932 |
Translation |
Target ORF information:
Target ORF information:
|
NM_144642.5 |
1 | ATGTGTATGG TGATATTTGC TCCGCTTTTT GCAATCTTTG CATTTGCAAC ATGCGGTGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu31866 | |
Clone ID Related Accession (Same CDS sequence) | NM_001130003.2 , NM_001130003.1 | |
Accession Version | NM_001130003.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 858bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-09-25 | |
Organism | Homo sapiens(human) | |
Product | synaptoporin isoform 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC099545.2, AC099056.2 and AC104436.2. On Nov 22, 2018 this sequence version replaced NM_001130003.1. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR3476690.778858.1, SRR1803611.151088.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968832, SAMEA2142586 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## MANE Ensembl match :: ENST00000478300.6/ ENSP00000418994.1 RefSeq Select criteria :: based on conservation, expression ##RefSeq-Attributes-END## COMPLETENESS: full length. |
1 | ATGGACCCTG TGAGTCAGCT GGCCTCTGCG GGCACCTTCC GGGTGCTGAA GGAGCCCCTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001123475.1 |
CDS | 227..1084 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001130003.2 |
1 | ATGGACCCTG TGAGTCAGCT GGCCTCTGCG GGCACCTTCC GGGTGCTGAA GGAGCCCCTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu31866 | |
Clone ID Related Accession (Same CDS sequence) | NM_001130003.2 , NM_001130003.1 | |
Accession Version | NM_001130003.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 858bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-10-01 | |
Organism | Homo sapiens(human) | |
Product | synaptoporin isoform 1 | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AC099545.2, AC099056.2 and AC104436.2. Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: SRR1660807.9343.1, SRR1660805.96587.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA1968832, SAMEA2142586 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGGACCCTG TGAGTCAGCT GGCCTCTGCG GGCACCTTCC GGGTGCTGAA GGAGCCCCTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001123475.1 |
CDS | 297..1154 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001130003.1 |
1 | ATGGACCCTG TGAGTCAGCT GGCCTCTGCG GGCACCTTCC GGGTGCTGAA GGAGCCCCTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu93815 | |
Clone ID Related Accession (Same CDS sequence) | XM_017005731.1 | |
Accession Version | XM_017005731.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 906bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | synaptoporin isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGAAAACAA AGAAACTCAT CCAAAGTTTC TCTGCAAATA CATGTTACAA AGAGTGTTAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_016861220.1 |
CDS | 15..920 |
Translation |
Target ORF information:
Target ORF information:
|
XM_017005731.1 |
1 | ATGAAAACAA AGAAACTCAT CCAAAGTTTC TCTGCAAATA CATGTTACAA AGAGTGTTAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu93816 | |
Clone ID Related Accession (Same CDS sequence) | XM_017005732.2 , XM_017005732.1 | |
Accession Version | XM_017005732.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 669bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-12-05 | |
Organism | Homo sapiens(human) | |
Product | synaptoporin isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process On Mar 26, 2018 this sequence version replaced XM_017005732.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Updated annotation Annotation Name :: Homo sapiens Updated Annotation Release 109.20191205 Annotation Version :: 109.20191205 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.3 Annotation Method :: Best-placed RefSeq; propagated RefSeq model Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGACCCTG TGAGTCAGCT GGCCTCTGCG GGCACCTTCC GGGTGCTGAA GGAGCCCCTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_016861221.1 |
CDS | 253..921 |
Translation |
Target ORF information:
Target ORF information:
|
XM_017005732.2 |
1 | ATGGACCCTG TGAGTCAGCT GGCCTCTGCG GGCACCTTCC GGGTGCTGAA GGAGCCCCTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OHu93816 | |
Clone ID Related Accession (Same CDS sequence) | XM_017005732.2 , XM_017005732.1 | |
Accession Version | XM_017005732.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 669bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-06-05 | |
Organism | Homo sapiens(human) | |
Product | synaptoporin isoform X2 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_000003.12) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Homo sapiens Annotation Release 108 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## |
1 | ATGGACCCTG TGAGTCAGCT GGCCTCTGCG GGCACCTTCC GGGTGCTGAA GGAGCCCCTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_016861221.1 |
CDS | 297..965 |
Translation |
Target ORF information:
Target ORF information:
|
XM_017005732.1 |
1 | ATGGACCCTG TGAGTCAGCT GGCCTCTGCG GGCACCTTCC GGGTGCTGAA GGAGCCCCTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome-wide association study of maternal and inherited effects on left-sided cardiac malformations. |
Cloning and sequence analysis of the human cDNA encoding the synaptoporin (delta), a highly conservative synaptic vesicle protein. |
Tyrosine nitration of a synaptic protein synaptophysin contributes to amyloid beta-peptide-induced cholinergic dysfunction. |
Synaptic vesicle protein synaptoporin is differently expressed by subpopulations of mouse hippocampal neurons. |
Expression of the synaptophysin gene family is not restricted to neuronal and neuroendocrine differentiation in rat and human. |